Results 121 to 130 of about 209,210 (339)

Efficacy of Eribulin Monotherapy in Patients With Unresectable and/or Metastatic Adenoid Cystic Carcinoma Receiving Platinum‐Based Therapy

Head &Neck, EarlyView.
ABSTRACT Background Adenoid cystic carcinoma (ACC) is the second most common and treatment‐resistant salivary gland carcinoma (SGC). Although platinum‐based therapies are effective, the efficacy of eribulin, a microtubule inhibitor with an 18% response rate in a Phase II trial involving recurrent/metastatic SGC, in patients with advanced ACC after ...
Tomomi Sanomachi, Tatsunori Shimoi, Yuki Kojima, Hideaki Takahashi, Motoko Arakaki, Asuka Kawachi, Hitomi Sumiyoshi Okuma, Mai Hoshino, Munehiro Ito, Ayumi Saito, Shosuke Kita, Aiko Maejima, Tadaaki Nishikawa, Kazuki Sudo, Taisuke Mori, Yasuhiro Fujiwara, Kan Yonemori   +16 more
wiley   +1 more source

Megaloblastic anemia - A clinical spectrum and a hematological profile: The day-to-day public health problem

Medical Journal of Dr. D.Y. Patil University, 2016
Aims and Objectives: To know the various parameters and diagnostic approach of megaloblastic anemia. To know the age incidence and sex ratio. Materials and Methods: A hospital-based retrospective and prospective study was done for a period of 1-year ...
S Srikanth
doaj   +1 more source

Osteomyelitis: an unusual sequel to neutropenia. [PDF]

, 1967
L. R. I. Baker, M. C. Brain, J Miller, M. J. Raphael   +3 more
openalex   +1 more source

First‐Line Therapy in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma: A Retrospective, Multicenter, Real‐World Study

Head &Neck, EarlyView.
ABSTRACT Background In Europe, pembrolizumab with or without chemotherapy is the recommended first‐line treatment for recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC), with a combined positive score (CPS) ≥ 1. In France, the TPExtreme (TPEx) regimen is preferred for CPS < 1.
Alizée Simon, Cyril Abdeddaim, DucTrung Nguyen, Patrice Gallet, Didier Peiffert, Aurélien Lambert, Lionnel Geoffrois   +6 more
wiley   +1 more source

Normal Granulocyte Colony-forming Cells in the Bone Marrow of Yemenite Jews With Genetic Neutropenia [PDF]

, 1973
Uri Mintz, Leo Sachs
openalex   +1 more source

Prophylactic Versus Reactive (PvR) Feeding in Patients Undergoing (Chemo)radiation in Head and Neck Cancers: Results of a Phase III Randomized Controlled Trial

Head &Neck, EarlyView.
ABSTRACT Background Optimal feeding strategy (Prophylactic vs. Reactive) during Radiation Therapy (RT) for Head and Neck Cancers (HNC) remains to be established. Methods This phase III trial randomized (1:1) patients of HNC to prophylactic [nasogastric tube (NGT) placed at least 1 day before RT starting] versus reactive arm (NGT when required).
Sarbani Ghosh Laskar, Shwetabh Sinha, Meenakshi Jeeva, Meetakshi Gupta, Shreyasee Karmakar, Anuj Kumar, Samarpita Mohanty, Purabi Mahajan, Shivashankar Timmanpyati, Arun Balaji, Ashwini Budrukkar, Monali Swain, Faizalam Khan, Gouri Pantvaidya, Anuja Deshmukh, Deepa Nair, Devendra Chaukar, Prathamesh Pai, Shiva Thiagarajan, Richa Vaish, Vidisha Tuljapurkar, Pankaj Chaturvedi   +21 more
wiley   +1 more source

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

International Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner, Jayant Y. Gadrey, Scott A. Armstrong, Michael W. M. Kühn   +3 more
wiley   +1 more source

Cyclic Neutropenia: The Relationship Between Urine Granulocyte Colony Stimulating Activity and Neutrophil Count [PDF]

, 1973
Aroop Mangalik, William A. Robinson
openalex   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, EarlyView.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

Chronic neutropenia in childhood: experience of a tertiary center

Jornal de Pediatria
Objective: To assess the prevalence of chronic neutropenia (CN) and the clinical profile of patients with CN aged up to 18 years, followed in the pediatric hematology, rheumatology, or immunology outpatient clinic of a tertiary medical center from May 1,
Letícia Matushita, Elvis Terci Valera, Davi Casale Aragon, Carlos Alberto Scridelli, Persio Roxo-Junior, Luciana Martins de Carvalho   +5 more
doaj