Results 11 to 20 of about 274,076 (393)

Neutropenia as an adverse event following vaccination : results from randomized clinical trials in healthy adults and systematic review [PDF]

PLoS ONE, 2016
Background : In the context of early vaccine trials aimed at evaluating the safety profile of novel vaccines, abnormal haematological values, such as neutropenia, are often reported.
Aerssens, Annelies, Anemona, Alessandra, Bodinham, Caroline L, Groth, Nicola, Launay, Odile, Leroux-Roels, Geert, Lewis, David, Loulergue, Pierre, Muturi-Kioi, Vincent, Podda, Audino, Saul, Allan   +10 more
core   +5 more sources

Hematopoietic stem cell boost for persistent neutropenia after CAR T-cell therapy: a GLA/DRST study

Blood Advances, 2022
Key Points • HSCBs for persistent neutropenia showed recovery or sustained neutrophil improvement in 84% of patients.• HSCBs given early and even for moderate neutropenia but high risk for infection showed excellent outcome.
N. Gagelmann, G. Wulf, J. Duell, B. Glass, P. V. Heteren, B. von Tresckow, Monika Fischer, O. Penack, F. Ayuk, H. Einsele, U. Holtick, Julia Thomson, P. Dreger, N. Kröger   +13 more
semanticscholar   +1 more source

Heterozygous Variants of CLPB are a Cause of Severe Congenital Neutropenia.

Blood, 2021
Severe congenital neutropenia (SCN) is an inborn disorder of granulopoiesis. Approximately one-third of cases do not have a known genetic cause. Exome sequencing of 104 persons with congenital neutropenia identified heterozygous missense variants of CLPB
J. Warren, Ryan R. Cupo, Peeradol Wattanasirakul, D. Spencer, A. Locke, Vahagn Makaryan, A. Bolyard, Meredith L Kelley, Natalie L Kingston, J. Shorter, C. Bellanné-Chantelot, J. Donadieu, D. Dale, D. Link   +13 more
semanticscholar   +1 more source

Treating neutropenia and neutrophil dysfunction in glycogen storage disease IB with an SGLT2-inhibitor.

Blood, 2020
Neutropenia and neutrophil dysfunction cause serious infections and inflammatory bowel disease in glycogen storage disease Ib (GSD-Ib). Our discovery that accumulating 1,5-anhydroglucitol-6-phosphate causes neutropenia in a G6PC3-deficient mouse model ...
S. Wortmann, J. V. Van Hove, T. Derks, N. Chevalier, Vijaya Knight, A. Koller, E. Oussoren, J. Mayr, F. V. van Spronsen, F. Lagler, Sommer Gaughan, E. Van Schaftingen, M. Veiga-da-Cunha   +12 more
semanticscholar   +1 more source

Severe Congenital Neutropenia

Handbook of Tumor Syndromes, 2020
Severe congenital neutropenia is a condition that causes affected individuals to be prone to recurrent infections. People with this condition have a shortage (deficiency) of neutrophils, a type of white blood cell that plays a role in inflammation and in
L. W. Moreland
semanticscholar   +1 more source

NEUTROPENIA IN PEDIATRIC PRACTICE: ETIOLOGY, PATHOGENESIS, CLASSIFICATION, DIAGNOSIS, TREATMENT (LITERATURE REVIEW AND OWN OBSERVATIONS)

Вісник проблем біології і медицини, 2020
The article is devoted to the problem of diagnosis and treatment of neutropenic conditions in children. A literary review of the modern understanding of the etiology, pathogenetic variants, classification, course, clinical picture, observation and ...
Koniushevska A. A., Parkhomenko T. A., Balychevtseva I. V., Tуmoshуna O. V., Akуmova L. G.   +4 more
doaj   +1 more source

Etiologi Demam Neutropenia pada Anak dengan Keganasan dan Penggunaan Skor Klasifikasi Rondinelli

Sari Pediatri, 2016
Latar belakang. Pasien anak dengan keganasan dapat mengalami episode demam neutropenia. Pada demam neutropenia, di tiap pusat pelayanan kesehatan, etiologi bakterimia berbeda dan berubah secara periodik.
Adrieanta Adrieanta, Endang Windiastuti, Setyo Handryastuti   +2 more
doaj   +1 more source

Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update.

Journal of Clinical Oncology, 2018
Purpose To provide an updated joint ASCO/Infectious Diseases Society of American (IDSA) guideline on outpatient management of fever and neutropenia in patients with cancer.
R. Taplitz, E. Kennedy, E. Bow, J. Crews, C. Gleason, D. Hawley, A. Langston, L. Nastoupil, M. Rajotte, K. Rolston, L. Strasfeld, C. Flowers   +11 more
semanticscholar   +1 more source

Sepsis and septic shock in patients with malignancies : a Groupe de Recherche Respiratoire en Réanimation Onco-Hématologique study [PDF]

, 2020
Objectives: Cancer affects up to 20% of critically ill patients, and sepsis is one of the leading reasons for ICU admission in this setting. Early signals suggested that survival might be increasing in this population. However, confirmation studies have
Azoulay, Elie, Benoit, Dominique, Bisbal, Magali, Borcoman, Edith, Bruneel, Fabrice, Darmon, Michaël, Hourmant, Yannick, Kouatchet, Achille, Legrand, Matthieu, Lemiale, Virginie, Mayaux, Julien, Meert, Anne-Pascale, Mirouse, Adrien, Mokart, Djamel, Nyunga, Martine, Pons, Stéphanie, Pène, Frédéric, Tudesq, Jean-Jacques, Zafrani, Lara   +18 more
core   +2 more sources

Costs associated with febrile neutropenia in solid tumor and lymphoma patients - an observational study in Singapore. [PDF]

, 2014
BackgroundThe primary objective was to describe the total direct inpatient costs among solid tumor and lymphoma patients with chemotherapy-induced febrile neutropenia (FN) and the factors that were associated with higher direct cost.
A Bosly, A Chan, A Ihbe-Heffinger, AG Freifeld, Alexandre Chan, B Dulisse, C O’Brien, CL Bennett, GH Lyman, GH Lyman, GH Lyman, H Khalili, J Klastersky, JI Mayordomo, Li Yang Hsu, LM Poon, M Wong, Mabel Wong, MB Schilling, NM Kuderer, SL Michels, SY Liou, V Caggiano, Xiao Jun Wang, YP Zhou   +24 more
core   +2 more sources