Results 231 to 240 of about 220,141 (335)

Neutropenia management

Annals of Oncology, 2006
openaire   +2 more sources

Phase 1/2 Study of Crizotinib in Children With Relapsed/Refractory ALK‐Positive Anaplastic Large Cell Lymphoma or Neuroblastoma in Japan

Cancer Science, EarlyView.
The safety and antitumor activity of crizotinib at a dose of 165 mg/m2 BID were evaluated in 16 patients with ALK‐positive ALCL in Japan. The most common grade 3 or 4 adverse event was neutropenia. The steady‐state Cmax and AUCtau of crizotinib at 165 mg/m2 BID were higher than expected. The objective response rate was 72.7% (90% CI, 43.6%–92.1%) among
Tetsuya Mori, Akiko Kada, Tomoo Osumi, Daisuke Tomizawa, Yuhki Koga, Reiji Fukano, Kengo Takeuchi, Ukihide Tateishi, Osamu Miyazaki, Ryuta Asada, Akiko M. Saito, Kei Fukuhara, Masahiro Sekimizu   +12 more
wiley   +1 more source

Carbapenems and febrile neutropenia [PDF]

, 2016
S. Alfandari, Céline Berthon, Florence Ader   +2 more
openalex   +1 more source

Compound Library Screening Identified Cladribine as a Novel Radiosensitizer for Prostate Cancer

Cancer Science, EarlyView.
The combination of cladribine and irradiation significantly suppressed the growth of DU145‐derived tumors compared with the DMSO plus irradiation group in the mouse model. In addition, it also elevated the percentage of γH2AX‐positive cells after irradiation.
Toshiki Oka, Koji Hatano, Shohei Katsuki, Tomohiro Kanaki, Shunsuke Inoguchi, Masaru Tani, Akihiro Yoshimura, Yuki Horibe, Yutong Liu, Nesrine Sassi, Yohei Okuda, Akinaru Yamamoto, Toshihiro Uemura, Gaku Yamamichi, Yu Ishizuya, Takuji Hayashi, Yoshiyuki Yamamoto, Taigo Kato, Atsunari Kawashima, Keisuke Tamari, Bangzhong Lin, Akiyoshi Tani, Kazutake Tsujikawa, Yutaka Takahashi, Kazuhiko Ogawa, Shawn E. Lupold, Norio Nonomura   +26 more
wiley   +1 more source

Severe Congenital Neutropenia in a Newborn Caused by a Novel Mutation in the <i>ELANE</i> Gene-First Report From North Macedonia and a Literature Review: A Case Report. [PDF]

Case Rep Pediatr
Zdraveska N, Trajkovska T, Jovanovska A, Hasani A, Hristova MK.   +4 more
europepmc   +1 more source

Congenital Neutropenia: In Vitro Growth of Colonies Mimicking the Disease

, 1973
P L'esperance, Richard D. Brunning, Robert A. Good   +2 more
openalex   +2 more sources

Congenital neutropenias

Hematology, 2005
openaire   +2 more sources

IAP Antagonists Selectively Eliminate Therapy‐Induced Senescent Cancer Cells via TNFα‐Independent Apoptosis

Cancer Science, EarlyView.
Upon chemotherapy, a subset of cancer cells enters a senescent state, referred to as TIS. When IAP antagonists are administered, TIS cells are selectively eliminated through TNFα‐independent apoptosis. TNFα secreted by TIS cancer cells may also act in a paracrine manner to enhance extrinsic apoptosis in neighboring non‐senescent cancer cells.
Hiroaki Ochiiwa, Takeshi Wakasa, Yuki Kataoka, Koji Ando, Eiji Oki, Yoshihiko Maehara, Makoto Iimori, Hiroyuki Kitao   +7 more
wiley   +1 more source

Southern African HIV Clinicians Society guideline for the prevention, diagnosis and management of cryptococcal disease among HIV-infected persons: 2019 update. [PDF]

, 2019
Black, J, Boulware, D, Boyles, T, Chiller, T, Dawood, H, Dlamini, S, Govender, NP, Harrison, TS, Ive, P, Jarvis, J, Karstaedt, A, Madua, MC, Mangena, P, Meintjes, G, Menezes, C, Moosa, M-YS, Motlekar, Z, Nel, J, Potgieter, S, Rabie, H, Reddy, D, Shroufi, A, Stacey, SL, Tsitsi, M, van Cutsem, G, Variava, E, Venter, M, Wake, R, Wilson, D   +28 more
core   +2 more sources

Brentuximab vedotin and radiotherapy for CD30‐positive cutaneous T‐cell lymphoma – a retrospective multicenter analysis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives While brentuximab vedotin (BV) and radiotherapy (RTx) are established treatment options for CD30‐positive cutaneous T‐cell lymphoma (CTCL), data on their simultaneous or sequential use regarding efficacy and tolerability remain scarce.
Patrick Schummer, Caroline Glatzel, Philipp Schrüfer, Ingulf Lawrenz, Gabor Dobos, Ulrike Wehkamp, Svea Hüning, René Stranzenbach, Jan P. Nicolay, Matthias Goebeler, Marion Wobser   +10 more
wiley   +1 more source