Results 81 to 90 of about 274,076 (393)

Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification. [PDF]

, 2020
Since 2013, the International Union of Immunological Societies (IUIS) expert committee (EC) on Inborn Errors of Immunity (IEI) has published an updated phenotypic classification of IEI, which accompanies and complements their genotypic classification ...
Ailal, Fatima, Al-Herz, Waleed, Bousfiha, Aziz, Casanova, Jean-Laurent, Chatila, Talal, Cunningham-Rundles, Charlotte, Etzioni, Amos, Franco, Jose Luis, Holland, Steven M, Jeddane, Leila, Klein, Christoph, Morio, Tomohiro, Ochs, Hans D, Oksenhendler, Eric, Picard, Capucine, Puck, Jennifer, Sullivan, Kathleen E, Tangye, Stuart G, Torgerson, Troy R   +18 more
core  

Abemaciclib in Combination with Single-Agent Options in Patients with Stage IV Non–Small Cell Lung Cancer: A Phase Ib Study [PDF]

, 2018
Purpose: Abemaciclib, a dual inhibitor of cyclin-dependent kinases 4 and 6, has demonstrated preclinical activity in non–small cell lung cancer (NSCLC).
Beckmann, Richard, Garrido, Pilar, Goldman, Jonathan W., Gutierrez, Martin, Hossain, Anwar, Jalal, Shadia, John, William J., Johnston, Erica L., Kambhampati, Siva Rama Prasad, Kelly, Karen, Kim, Edward S., Mahadevan, Daruka, Paz-Ares, Luis G., Provencio, Mariano, Schaefer, Eric, Shaheen, Monte, Turner, P. Kellie   +16 more
core   +1 more source

Carbapenems and febrile neutropenia [PDF]

Clinical Microbiology and Infection, 2017
International ...
Alfandari, S., Berthon, C., Ader, Florence   +2 more
openaire   +5 more sources

Evaluating the Effectiveness of Artificial Intelligence in Predicting Adverse Drug Reactions among Cancer Patients: A Systematic Review and Meta-Analysis [PDF]

2023 IEEE International Conference Challenges and Innovations on TIC (I2CIT), Hammamet, Tunisia, 2023, pp. 1-8
Adverse drug reactions considerably impact patient outcomes and healthcare costs in cancer therapy. Using artificial intelligence to predict adverse drug reactions in real time could revolutionize oncology treatment. This study aims to assess the performance of artificial intelligence models in predicting adverse drug reactions in patients with cancer.
arxiv   +1 more source

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

Molecular Psychiatry, 2016
The antipsychotic clozapine is uniquely effective in the management of schizophrenia; however, its use is limited by its potential to induce agranulocytosis.
Citation Legge, M. Hamshere, S. Ripke, A. Pardiñas, J. Goldstein, E. Rees, A. Richards, S. Legge, M. Hamshere, S. Ripke, A. Pardiñas, J. Goldstein, E. Rees, A. Richards, G. Leonenko, L. Jorskog, Clozapine-Induced Agranulocytosis Consortium, K. Chambert, D. A. Collier, G. Genovese, I. Giegling, P. Holmans, Adalbjorg Jonasdottir, G. Kirov, S. Mccarroll, J. MacCabe, K. Mantripragada, J. Moran, B. Neale, H. Stefánsson, D. Rujescu, M. J. Daly, Patrick F. Sullivan, M. Owen, M. O. O’ Donovan, J. Walters, W. Manor, T. R. James, Walters, F. Jarskog, C. Hilliard, A. Alfirevic, L. Duncan, D. Fourches, Hailiang Huang, M. Lek, K. Shianna, J. Szatkiewicz, A. Tropsha, E. J. van den Oord, I. Cascorbi, M. Dettling, E. Gazit, D. Goff, A. Holden, D. Kelly, A. K. Malhotra, J. Nielsen, M. Pirmohamed, T. Werge, D. Levy, R. Josiassen, James L. Kennedy, J. Lieberman, Franzcp   +64 more
semanticscholar   +1 more source

Long‐Term Survival of Two Versus Three Courses of Preoperative Cisplatin and Fluorouracil Plus Docetaxel for Locally Advanced Esophageal Cancer: A Multicenter Randomized Phase II Trial

Annals of Gastroenterological Surgery, EarlyView.
This multi‐institutional, randomized, phase II trial aimed to investigate the long‐term survival outcomes of two versus three courses of DCF for locally advanced esophageal squamous cell carcinoma (ESCC). The 5‐year overall survival and progression‐free survival rates for the three and two course groups were 70.7% vs. 63.8% (hazard ratio (HR) = 0.91, p 
Takahito Sugase, Hiroshi Miyata, Takashi Kanemura, Norihiro Matsuura, Tomoki Makino, Makoto Yamasaki, Koji Tanaka, Kotaro Yamashita, Kota Momose, Osamu Shiraishi, Keijiro Sugimura, Masaaki Motoori, Kazumasa Fujitani, Atsushi Takeno, Motohiro Hirao, Yutaka Kimura, Taroh Satoh, Masahiko Yano, Yuichiro Doki, Takushi Yasuda   +19 more
wiley   +1 more source

Congenital neutropenia: diagnosis, molecular bases and patient management

Orphanet Journal of Rare Diseases, 2011
The term congenital neutropenia encompasses a family of neutropenic disorders, both permanent and intermittent, severe (
Chantelot Christine, Beaupain Blandine, Mahlaoui Nizar, Fenneteau Odile, Donadieu Jean   +4 more
doaj   +1 more source

Cabazitaxel in the treatment of metastatic castration-resistant prostate cancer: patient selection and special considerations. [PDF]

, 2017
Cabazitaxel is an effective chemotherapeutic agent used in the treatment of metastatic castration-resistant prostate cancer (mCRPC) refractory to docetaxel.
Hoffman-Censits, Jean, Patel, Sheel
core   +3 more sources

Significance of Neoadjuvant S‐1‐Based Chemotherapy for Older Patients With Locally Advanced Gastric Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Neoadjuvant chemotherapy (NAC) has been extensively developed for locally advanced gastric cancer (GC). In Asia, S‐1‐based regimens, such as docetaxel, oxaliplatin, and S‐1 (DOS) and S‐1 and oxaliplatin (SOX), are expected to become the standard of care.
Kota Kawabata, Takuro Saito, Yukinori Kurokawa, Kazuyoshi Yamamoto, Tsuyoshi Takahashi, Koji Tanaka, Tomoki Makino, Kiyokazu Nakajima, Hidetoshi Eguchi, Yuichiro Doki   +9 more
wiley   +1 more source

Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. [PDF]

, 2014
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus ...
Butcher, Brad, Carlson, Adam Q, Graf, Jonathan, Imboden, John B, Jen, Kuang-Yu, Sam, Ramin, Tuot, Delphine S   +6 more
core   +2 more sources