Results 241 to 250 of about 165,043 (309)

Neutrophil-to-lymphocyte ratio as a prognostic predictor in adrenocortical carcinoma: a retrospective cohort study stratified by cortisol secretion status. [PDF]

Transl Cancer Res
Zhang T, Dong R, Li A, Liu B, Sun Z, Kou X, Li M, Zhang J, Shang J, Shi B, Guo H, Wu D, Qiang W.   +12 more
europepmc   +1 more source

Reactive Oxygen Species–Induced Modifications of Fibrin Clots as a Link Between Immune Responses and Atherothrombosis in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Cardiovascular events are major determinants of morbidity and mortality in systemic lupus erythematosus (SLE), particularly in patients with renal involvement. Although oxidative stress has been implicated in driving vascular and renal damage in SLE, the specific mechanisms remain unclear.
Matteo Becatti, Giacomo Emmi, Alessandra Bettiol, Amanda Mannucci, Flavia Rita Argento, Eleonora Fini, Serena Borghi, Francesca Nencini, Maria Nicastro, Irene Mattioli, Elena Silvestri, Augusto Vaglio, Domenico Prisco, Claudia Fiorillo   +13 more
wiley   +1 more source

Neutrophil-to-Lymphocyte Ratio as a Promising Non-Invasive Biomarker for Diagnosis of Feline Idiopathic Cystitis in Cats. [PDF]

Animals (Basel)
Yang J, Zhang X, Zhang W, Zhang Y, Shi L, Zeng L, Qiao M, Shi H.   +7 more
europepmc   +1 more source

Population pharmacokinetics and exposure–response analysis of durvalumab in patients with resectable stage II to IIIB (N2) NSCLC in the phase III AEGEAN study

British Journal of Clinical Pharmacology, EarlyView.
Aims In the AEGEAN study, perioperative durvalumab plus platinum‐based neoadjuvant chemotherapy for patients with resectable stage II to IIIB (N2) non‐small‐cell lung cancer (NSCLC) demonstrated a favourable benefit–risk profile. This study evaluated population pharmacokinetics (PopPK) and exposure–response (ER) relationships of durvalumab in patients ...
Xiaoying Zhao, Junjie Ding, Jiajia Zhao, Ling Zhang, Aburough Abegesah, Yu‐qian Zhang, Cathy O'Brien, Gary J. Doherty, Allen C. Chen, KyoungSoo Lim, Song Ren, Peiming Ma, Diansong Zhou   +12 more
wiley   +1 more source

A Study of the Association of Cerebrospinal Fluid Neutrophil-to-Lymphocyte Ratio with Severity and Mortality in Patients with Tuberculous Meningitis. [PDF]

Ann Indian Acad Neurol
Mateen S, Siddiqi Z, Singh S, Singh A, Khan M.   +4 more
europepmc   +1 more source

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Neutrophil-to-Lymphocyte Ratio and Fibroblast Growth Factor 21: Their Role in Early Cardiovascular Involvement in Rheumatoid Arthritis. [PDF]

J Clin Med
Ciołkiewicz M, Kuryliszyn-Moskal A, Jabłońska E, Ratajczak-Wrona W, Wojciuk M, Klimiuk PA.   +5 more
europepmc   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Predictive value of derived neutrophil-to-lymphocyte ratio for immune checkpoint inhibitor outcomes in advanced gastric cancer. [PDF]

Medicine (Baltimore)
Cao Y, Gong H, Han G, Zhang Y, Zhang Y, Zhang X.   +5 more
europepmc   +1 more source

Targeting both tumour-associated CXCR2+ neutrophils and CCR2+ macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma [PDF]

, 2018
Belt, Brian A, Cullinan, Darren R, DeNardo, David G, Fields, Ryan C, Gillanders, William E, Goedegebuure, Peter, Han, Booyeon J, Hawkins, William G, Jacobs, Ryan C, Linehan, David C, Nywening, Timothy M, Panni, Roheena Z, Patel, Ankit A, Sanford, Dominic E, Ye, Jian   +14 more
core   +1 more source