Results 171 to 180 of about 688,534 (290)

Neutrophil CD14 is a driver and a therapeutic target for deep vein thrombosis. [PDF]

Blood Adv
Pandey N, Kaur H, Mitra R, Chandaluri L, Shaaban N, Martinez A, Kidder E, Anand SK, Butler ME, Zhang X, Goswami D, Frausto L, Kumar D, Pandit R, Das S, Rohilla S, Mohajan S, Male G, Huque A, Salem AR, Magdy T, Gross DS, Stokes KY, Orr AW, Tousif S, Yurdagul A, Rom O, Dhanesha N.   +27 more
europepmc   +1 more source

Interaction between the respiratory burst activity of neutrophil leukocytes and experimentally induced escherichia-coli mastitis in cows [PDF]

, 1990
Burvenich, Christian, Heyneman, Roger, Vercauteren, R   +2 more
core   +2 more sources

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

Advanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi, Ming‐yang Wu, Jin‐quan Liu, Cuicui Tian, Li Ma, Xue‐mei Zhou, Ze‐Hao Sun, Zhi‐yong Xu, Run‐dong Zhang, Shan‐yuan Ye, Li‐ming Huang, Yan Wang, Jing‐shu Xiong, Wen‐bo Bu, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +16 more
wiley   +1 more source

High altitude-mediated immune remodeling accelerates aging. [PDF]

Sci Adv
Xiao Y, Li Y, Mao Y, Jin Z, Sun M, Wang X, Zhao G, Song Y, Li J, Zhang Z, Liu L, Feng S, Liu M, Chen Z, Guo X, Yu R, Li H, Yang C, Luo C, Li J, Zhao Z, Zhang J, Cai L, Ma H, Li S, Li S, Xu F, Xin G, Jiang Q, Huang F, Kang L, Zhang C.   +31 more
europepmc   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Tumor-associated neutrophils in pancreatic ductal adenocarcinoma: mechanisms and therapeutic targeting. [PDF]

Front Immunol
Wu X, Zhu W, Chen W, Ruan L.
europepmc   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Neutrophil myeloperoxidase index in juvenile dogs with parvoviral enteritis. [PDF]

J Vet Diagn Invest
Loubser LC, Botha WJ, Rautenbach Y, Celliers A.   +3 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Modic Change Bone Marrow Neutrophils Are Activated and Degrade Cartilage Endplates. [PDF]

JOR Spine
Heggli I, Mengis T, Devan J, Herger N, Farshad M, Habib M, Ames CP, Distler O, Fields AJ, Dudli S.   +9 more
europepmc   +1 more source