Results 221 to 230 of about 548,170 (252)

CD177⁺ neutrophils drive extracellular matrix remodelling and HGF-alpha release in ALPPS-induced liver regeneration. [PDF]

Gut
Yan J, Huang A, Zhang S, Yao N, Huang J, Jiang Z, Wang J, Chen F, Yu Q, Cheng J, Zhang S, Li T, Gao R, Miao R, Luo R, Zhou S, Ji Y, Wang Z, Gao D, Ding Z, Tang Z, Fan J, Esteban MA, Schlitt HJ, Yang X, Zhou J.   +25 more
europepmc   +1 more source

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

Advanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang, Binxiang Zhu, Yuzhi He, Yang Tian, Honglei Kang, Shian Hu, Pengju Wang, Yong Xu, Zhuowei Lei, Peijun Qi, Hao Yang, Yang Lin, Yimin Dong, Feng Li, Hanfeng Guan   +14 more
wiley   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Temporal coupling of cortisol and immune cell responses in acute psychosocial stress. [PDF]

Brain Behav Immun Health
Grönvall H, Tabrizi F, Abdelhalim S, Rosén J, Hirsch J, Åhs F.   +5 more
europepmc   +1 more source

Complete Blood Count Parameters and Hemogram-Derived Inflammatory Indices in Adolescent Pregnancy: A Retrospective Comparative Cohort Study with Exploratory Machine-Learning Analyses. [PDF]

J Clin Med
Bekmezci M, Bülbül R, Genç ŞÖ, Erdal H.   +3 more
europepmc   +1 more source

Neutrophils in Kidney Disease: Linking Neutrophil Function and Microenvironment to Therapeutic Targets. [PDF]

J Inflamm Res
Ku J, Flora KK, Steiger S, Anders HJ.
europepmc   +1 more source

NLRP3 Deficiency Enhances Neutrophil Motility and Phagocytic Function in the Inflamed Kidney. [PDF]

Immune Netw
Yang H, Park KM, Lim KY, Hyun YM.
europepmc   +1 more source

Beyond Type 2 Inflammation: Why Neutrophils Deserve a Central Role in Refractory Airway Disease. [PDF]

Clin Exp Allergy
Hao Y, Zhou Y, Chen J.
europepmc   +1 more source

Evaluation of ten composite inflammatory indicators for sarcopenia in type 2 diabetes mellitus. [PDF]

Front Endocrinol (Lausanne)
Wei W, Zhong L, Cao H, Zhong F, Lin H, Chen H, Cao L, Lin R, Wen S.   +8 more
europepmc   +1 more source