Results 151 to 160 of about 847,167 (258)

An Injectable Magneto-Responsive Periosteum Reprograms Neutrophil Extracellular Trap Formation for Osteomyelitis Treatment. [PDF]

Adv Mater
Wu Y, Lin Z, Zhou J, Shen C, Fu Y, Wang K, Shen S, Su P, He X, Ji X, Wang W, Qi Y, Feng G.   +12 more
europepmc   +1 more source

Reframing Technology and Ethics in Corneal Xenotransplantation: A Scoping Review of Standards and Safety in Ophthalmology

Health Care Science, EarlyView.
Bringing attention to the moral dilemmas raised by xenotransplantation and the continuous creation of standardized frameworks for donor technology and biosafety risk management, with a focus on striking a balance between patient safety, medical innovation, and ethical obligation.
Sankhajyoti Saha, Moubani Dutta, Agnihiya Bosu   +2 more
wiley   +1 more source

Neutrophil Elastase Inhibition Prevents Neutrophil extracellular trap (NETs) Driven Autoimmune Glomerulonephritis Without Off Target Immunosuppression 2256502

Introduction Neutrophils release Neutrophil Extracellular Traps (NETs) as a final defense to trap and kill pathogens. In sterile inflammation, however, NETs become injurious, exposing over 70 autoantigens that drive tissue damage ...
Kim O’Sullivan, Lu Lu, Oneli Kulatunge, Andre Espiritu, Belinda Thomas   +4 more
core   +1 more source

Organ‐Resolved Host Proteomic and Post‐Translational Modification Landscapes in a Mouse Model of Talaromyces marneffei Infection

iMetaMed, EarlyView.
We presented an organ‐resolved, multiple PTM remodeling atlas of systemic T. marneffei infection, integrating quantitative proteome, phosphoproteome, ubiquitinome, acetylome, and lactylome data across the liver, lung, and spleen. The atlas delineated organ‐specific PTM signatures and a functional convergence of divergent modification types on immune ...
Wudi Wei, Shiyi Lai, Xiaotao He, Xiaoting Wei, Xiaoting Xie, Weihong Huang, Baili Zhan, Meng Zhang, Zongxiang Yuan, Rongfeng Chen, Jingzhen Lai, Yuyuan Huang, Kang Li, Sanqi An, Li Ye, Hao Liang, Junjun Jiang   +16 more
wiley   +1 more source

Proteolytic neutralization of extracellular histones by neutrophil elastase is enhanced by heparin

Background: Release of extracellular histones during cell death or neutrophil extracellular trap formation is linked to initiation and progression of several acute inflammatory diseases.
Huckriede, Joram, Wichapong, Kanin; id_orcid, Reutelingsperger, Chris P M, Nicolaes, Gerry A F; id_orcid, van de Poll, Marcel C G, Keulen, Gwen M   +5 more
core   +1 more source

Neutrophil extracellular trap (NET)-related index as an indicator of periprosthetic joint infection. [PDF]

J Bone Jt Infect
Cui T, Liang Y, Feng Z, Hao L, Zhang G, Ni M, Sheng J, Shangguan D, Chen J, Fu J.   +9 more
europepmc   +1 more source

Butyrate ameliorates acute‐on‐chronic liver failure by regulating macrophage polarization

iMetaOmics, EarlyView.
Multi‐omics profiling identifies progressive microbiota‐metabolism‐immunity axis dysfunction in acute‐on‐chronic liver failure (ACLF), characterized by gut dysbiosis, reduced butyrate production, intestinal barrier disruption, microbial translocation, and pro‐inflammatory macrophage polarization, thereby exacerbating hepatic inflammation and fibrosis ...
Jing Xiao, Hang You, Zongyi Liu, Yong Sun, Yu Zhang, Li Wei, Ning Ling, Hong Ren, Shiying Li, Peng Hu, Mingli Peng   +10 more
wiley   +1 more source

Stimulus-Induced Histone H3 Citrullination and Neutrophil Extracellular Trap Formation Are Impaired in Patients with Proliferative Diabetic Retinopathy. [PDF]

Biomedicines
Buentello-Volante B, Magaña-Guerrero FS, Magaña-Guerrero NA, Rodriguez-Loaiza JL, Vivanco-Rojas O, Domínguez-López A, Garfias Y.   +6 more
europepmc   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Neutrophil extracellular trap-associated responses are associated with tissue factor expression and coagulation abnormalities during anaphylaxis. [PDF]

Front Immunol
Huang Y, Xu S, Rong P, Wang D, Lu J.
europepmc   +1 more source