Results 181 to 190 of about 847,167 (258)

Lower airway dysbiosis in nontuberculous mycobacteria-positive bronchiectasis is associated with neutrophil extracellular trap-predominant severe phenotypes. [PDF]

Am J Respir Crit Care Med
Singh S, Darawshy F, Erlandson K, Narayana JK, Li Q, Li Y, Atandi I, Krolikowski K, Patel S, Collazo D, Mac Aogáin M, Gilmour A, Long M, Chang M, Hoque A, Schluger R, Kumar S, Chung CJ, Wong K, Porter G, Feng Y, Czachor A, McCormick C, Clementi E, Kyeremateng Y, Lukovnikova A, Harris D, Gomez S, Kain T, Kocak I, Singh R, Rodriguez C, Kwok B, Barnett C, Kugler M, Weiden MD, Nelson N, Natalini JG, Luglio D, Desvignes L, Gautam S, McGuire E, Gordon T, Sulaiman I, Tsay JJ, Basavaraj A, Wu BG, Kamelhar D, Addrizzo-Harris D, Chalmers JD, Chotirmall SH, Segal LN.   +51 more
europepmc   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

PROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima, Wilson Dias Segura, Leonardo Brogliato de Moraes, Reinaldo Souza Oliveira, Pedro Henrique Corteletti Manfio, Alison Felipe Alencar Chaves, Wagner Luiz Batista   +6 more
wiley   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell-Derived Microvesicles Alleviate Bronchopulmonary Dysplasia in Preterm Rats by Inhibiting Neutrophil Extracellular Trap Formation. [PDF]

Pediatr Discov
Lu Y, Tan W, Yang X, Luo T, Mei C, Bu H, Ma J, Gong C, Zhong L, Zhou O, Tian D.   +10 more
europepmc   +1 more source

Proteomic Analysis of Mixed Cell Membrane Extracts From Triple‐Negative Breast Cancer Cell Lines Revealed Broad Metabolic Reprogramming Associated With Tumor Progression

PROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca, Violeta Larios‐Serrato, María Luisa Labra‐Barrios, Emmanuel Ríos‐Castro, Carlos Alberto Castañón‐Sánchez, Rodolfo Moreno‐Castillo, Erika Beatriz Ángeles‐Morales, Juan Pedro Luna‐Arias   +7 more
wiley   +1 more source

Beneficial effects of antioxidants on neutrophil extracellular trap formation in atherosclerosis. [PDF]

Arch Med Sci
Dąbrowska-Zagroba D, Garley M, Ratajczak-Wrona W, Sawicka-Powierza J, Grubczak K, Radziwon P, Wołczyński S, Jabłońska E.   +7 more
europepmc   +1 more source

Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions

Portal Hypertension &Cirrhosis, EarlyView.
This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley   +1 more source

Tailored Ion Release of Polycaprolactone and Calcium Silicate Composite Fibers Attenuates Neutrophil Extracellular Trap Formation for Dentin-Pulp Complex Regeneration. [PDF]

Biomater Res
Ryu JH, Jiang ES, Lee E, Bae J, Moon W, Chung SH, Woo KM.   +6 more
europepmc   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Neutrophil Extracellular Trap Components Are Present in the Aqueous Humor of Glaucoma Patients. [PDF]

Transl Vis Sci Technol
Katz EA, Yang Y, Surenkhuu B, Dabre Z, Dammak A, Rao VR, Mun C, Pradeep A, Kim C, Aref AA, Bhat P, de la Cruz J, Kaja S, Jain S.   +13 more
europepmc   +1 more source

Natural Products Exhibit Therapeutic Potential in Treating Rheumatoid Arthritis by Targeting the PI3K/Akt Signaling Pathway

Phytotherapy Research, EarlyView.
This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren, Yige Wang, Wenjing Ma, Omachi Daniel Ogaji, Shujing Chen, Kunze Du, Xuemi Zhang, Bo Xu, Shanxing Zhai, Shiming Fang, Yanxu Chang   +10 more
wiley   +1 more source