Results 1 to 10 of about 19,957 (258)

Cyclic stretch enhances neutrophil extracellular trap formation [PDF]

open access: yesBMC Biology
Background Neutrophils, the most abundant leukocytes circulating in blood, contribute to host defense and play a significant role in chronic inflammatory disorders.
Manijeh Khanmohammadi   +7 more
doaj   +4 more sources

Mast Cell Tryptase Potentiates Neutrophil Extracellular Trap Formation [PDF]

open access: yesJournal of Innate Immunity, 2021
Previous research has indicated an intimate functional communication between mast cells (MCs) and neutrophils during inflammatory conditions, but the nature of such communication is not fully understood.
Gunnar Pejler   +6 more
doaj   +5 more sources

Histone Acetylation Promotes Neutrophil Extracellular Trap Formation [PDF]

open access: yesBiomolecules, 2019
Neutrophils undergo a unique form of cell death to generate neutrophil extracellular traps (NETs). It is well established that citrullination of histones (e.g., CitH3) facilitates chromatin decondensation during NET formation (NETosis), particularly ...
Hussein J. Hamam   +2 more
doaj   +4 more sources

Neutrophil Activation and Neutrophil Extracellular Trap Formation in Dialysis PatientsPlain-Language Summary [PDF]

open access: yesKidney Medicine, 2020
Rationale & Objective: The removal of metabolic waste by passing blood through synthetic tubing and membranes generates an immune response, even with the most biocompatible materials available.
Scott Bieber   +2 more
doaj   +3 more sources

Impaired neutrophil extracellular trap formation in β-thalassaemia/HbE [PDF]

open access: yesScientific Reports, 2022
Neutrophil dysfunction contributes to a high susceptibility to severe bacterial infection which is a leading cause of morbidity and mortality in β-thalassaemia/HbE, especially in splenectomised patients.
Rattanawan Thubthed   +7 more
doaj   +4 more sources

Inhibition of Peptidyl Arginine Deiminase-4 Prevents Renal Ischemia-Reperfusion-Induced Remote Lung Injury

open access: yesMediators of Inflammation, 2020
Ischemia reperfusion (IR) can lead to acute kidney injury and can be complicated by acute lung injury, which is one of the leading causes of acute kidney injury-related death.
Mingjun Du   +5 more
doaj   +1 more source

Activated Platelets Autocrine 5-Hydroxytryptophan Aggravates Sepsis-Induced Acute Lung Injury by Promoting Neutrophils Extracellular Traps Formation

open access: yesFrontiers in Cell and Developmental Biology, 2022
Excessive neutrophil extracellular trap (NET) formation is an important contributor to sepsis-induced acute lung injury (ALI). Recent reports indicate that platelets can induce neutrophil extracellular trap formation.
Yumeng Huang   +11 more
doaj   +1 more source

Influence of iron- and zinc-chelating agents on neutrophil extracellular trap formation

open access: yesCentral European Journal of Immunology, 2021
Release of neutrophil extracellular traps (NETs) is one of the neutrophils’ mechanisms involved in the response to infection. NETs are released from the cell in response to a biological or synthetic stimulus to entrap, immobilize and kill pathogens ...
Weronika Kuźmicka   +5 more
doaj   +1 more source

Ménage-à-trois: The ratio of bicarbonate to CO2 and the pH regulate the capacity of neutrophils to form NETs

open access: yesFrontiers in Immunology, 2016
In this study we identified and characterized the potential of a high ratio of bicarbonate to CO2 and a moderately alkaline pH to render neutrophils prone to undergo neutrophil extracellular trap (NET) formation.
Christian Maueröder   +14 more
doaj   +1 more source

PEGylation of Metal Oxide Nanoparticles Modulates Neutrophil Extracellular Trap Formation

open access: yesBiosensors, 2022
Novel metal oxide nanoparticle (NP) contrast agents may offer safety and functionality advantages over conventional gadolinium-based contrast agents (GBCAs) for cancer diagnosis by magnetic resonance imaging.
Hunter T. Snoderly   +5 more
doaj   +1 more source

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