Results 1 to 10 of about 36,600 (202)

Cyclic stretch enhances neutrophil extracellular trap formation [PDF]

open access: yesBMC Biology
Background Neutrophils, the most abundant leukocytes circulating in blood, contribute to host defense and play a significant role in chronic inflammatory disorders.
Manijeh Khanmohammadi   +7 more
doaj   +4 more sources

Diabetes Primes Neutrophils for Neutrophil Extracellular Trap Formation through Trained Immunity [PDF]

open access: yesResearch
Neutrophils are primed for neutrophil extracellular trap (NET) formation during diabetes, and excessive NET formation from primed neutrophils compromises wound healing in patients with diabetes.
Sanjeeb Shrestha   +14 more
doaj   +4 more sources

Mast Cell Tryptase Potentiates Neutrophil Extracellular Trap Formation [PDF]

open access: yesJournal of Innate Immunity, 2021
Previous research has indicated an intimate functional communication between mast cells (MCs) and neutrophils during inflammatory conditions, but the nature of such communication is not fully understood.
Gunnar Pejler   +6 more
doaj   +5 more sources

Impaired neutrophil extracellular trap formation in β-thalassaemia/HbE [PDF]

open access: yesScientific Reports, 2022
Neutrophil dysfunction contributes to a high susceptibility to severe bacterial infection which is a leading cause of morbidity and mortality in β-thalassaemia/HbE, especially in splenectomised patients.
Rattanawan Thubthed   +7 more
doaj   +4 more sources

Pyocyanin-enhanced neutrophil extracellular trap formation requires the NADPH oxidase. [PDF]

open access: yesPLoS ONE, 2013
Beyond intracellular killing, a novel neutrophil-based antimicrobial mechanism has been recently discovered: entrapment and killing by neutrophil extracellular traps (NETs).
Balázs Rada   +8 more
doaj   +4 more sources

Neutrophil Extracellular Traps Go Viral [PDF]

open access: yes, 2016
Neutrophils are the most numerous immune cells. Their importance as the first line of defense against bacterial and fungal pathogens is well described. In contrast, the role of neutrophils in controlling viral infections is less clear.
Assinger   +105 more
core   +8 more sources

Inhibition of Peptidyl Arginine Deiminase-4 Prevents Renal Ischemia-Reperfusion-Induced Remote Lung Injury

open access: yesMediators of Inflammation, 2020
Ischemia reperfusion (IR) can lead to acute kidney injury and can be complicated by acute lung injury, which is one of the leading causes of acute kidney injury-related death.
Mingjun Du   +5 more
doaj   +1 more source

Activated Platelets Autocrine 5-Hydroxytryptophan Aggravates Sepsis-Induced Acute Lung Injury by Promoting Neutrophils Extracellular Traps Formation

open access: yesFrontiers in Cell and Developmental Biology, 2022
Excessive neutrophil extracellular trap (NET) formation is an important contributor to sepsis-induced acute lung injury (ALI). Recent reports indicate that platelets can induce neutrophil extracellular trap formation.
Yumeng Huang   +11 more
doaj   +1 more source

Influence of iron- and zinc-chelating agents on neutrophil extracellular trap formation

open access: yesCentral European Journal of Immunology, 2021
Release of neutrophil extracellular traps (NETs) is one of the neutrophils’ mechanisms involved in the response to infection. NETs are released from the cell in response to a biological or synthetic stimulus to entrap, immobilize and kill pathogens ...
Weronika Kuźmicka   +5 more
doaj   +1 more source

Ménage-à-trois: The ratio of bicarbonate to CO2 and the pH regulate the capacity of neutrophils to form NETs

open access: yesFrontiers in Immunology, 2016
In this study we identified and characterized the potential of a high ratio of bicarbonate to CO2 and a moderately alkaline pH to render neutrophils prone to undergo neutrophil extracellular trap (NET) formation.
Christian Maueröder   +14 more
doaj   +1 more source

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