Results 171 to 180 of about 36,600 (202)

Salidroside ameliorates acute liver transplantation rejection in rats by inhibiting neutrophil extracellular trap formation. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Qin X, Wang H, Li Q, Hu D, Wang L, Zhou B, Liao R, Liu Y.   +7 more
europepmc   +1 more source

AOC3 accelerates lung metastasis of osteosarcoma by recruiting tumor-associated neutrophils, neutrophil extracellular trap formation and tumor vascularization. [PDF]

Heliyon
Qi L, Gao T, Bai C, Guo Z, Zhou L, Yang X, Fan Z, Zhang G.   +7 more
europepmc   +1 more source

Inhibition of ALOX12-12-HETE Alleviates Lung Ischemia-Reperfusion Injury by Reducing Endothelial Ferroptosis-Mediated Neutrophil Extracellular Trap Formation. [PDF]

Research (Wash D C)
Li C, Gao P, Zhuang F, Wang T, Wang Z, Wu G, Zhou Z, Xie H, Xie D, Zhao D, Wu J, Chen C.   +11 more
europepmc   +1 more source

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Dysregulated neutrophil extracellular traps formation in sepsis

Immunology, 2023
AbstractThe migration and antimicrobial functions of neutrophils seem to be impaired during sepsis and contribute to the dysregulation of immune responses and disease pathogenesis. However, the role of neutrophil extracellular traps (NETs) remains to be clarified.
Maria Mulet, Ruben Osuna‐Gómez, Carlos Zamora, Iris Artesero, Marc Arús, Paula Vera‐Artazcoz, Alejandra Cordón, Noelia Vilalta, Paula San‐José, Andrés Abril, Antoni Moliné, Indalecio Morán, Joaquín López‐Contreras, Silvia Vidal   +13 more
openaire   +2 more sources

TIMP1 Triggers Neutrophil Extracellular Trap Formation in Pancreatic Cancer

Cancer Research, 2021
Abstract Tumor-derived protein tissue inhibitor of metalloproteinases-1 (TIMP1) correlates with poor prognosis in many cancers, including highly lethal pancreatic ductal adenocarcinoma (PDAC). The noncanonical signaling activity of TIMP1 is emerging as one basis for its contribution to cancer ...
Benjamin Schoeps, Celina Eckfeld, Olga Prokopchuk, Jan Böttcher, Daniel Häußler, Katja Steiger, Ihsan Ekin Demir, Percy Knolle, Oliver Soehnlein, Dieter E. Jenne, Chris D. Hermann, Achim Krüger   +11 more
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Mechanical Ventilation Induces Neutrophil Extracellular Trap Formation

Anesthesiology, 2015
AbstractAbstract By creating lung injury in mice using intratracheal lipopolysaccharide and mechanical ventilation, the authors documented that neutrophil extracellular traps were formed when lipopolysaccharide was present during high tidal ventilation and could be treated with deoxyribonuclease I.
Christopher, Yildiz, Nades, Palaniyar, Gail, Otulakowski, Meraj A, Khan, Martin, Post, Wolfgang M, Kuebler, Keith, Tanswell, Rosetta, Belcastro, Azhar, Masood, Doreen, Engelberts, Brian P, Kavanagh   +10 more
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Role of PTEN in neutrophil extracellular trap formation

Molecular Immunology, 2015
NETosis has been associated with a particular mode of cell death although it is still controversial as to what extent autophagy is involved in NETosis. Class I/AKT/mTOR pathway is a key regulator of autophagy. PTEN tumor suppressor gene encodes a dual specificity phosphatase that antagonizes the phosphatidylinositol 3-kinase in class the I/AKT/mTOR ...
Shahram, Teimourian, Ehsan, Moghanloo
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Enhanced formation of neutrophil extracellular traps in Kawasaki disease

Pediatric Research, 2020
Neutrophils contribute to the clearance of pathogens through the formation of neutrophil extracellular traps (NETs) in a process known as NETosis, but the excessive release of NETs has been reported to be involved in the pathogenesis of various diseases, including vasculitis, by inducing tissue injury.
Yusuke Yoshida, Seiichiro Takeshita, Yoichi Kawamura, Takashi Kanai, Yuki Tsujita, Shigeaki Nonoyama   +5 more
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Singlet oxygen is essential for neutrophil extracellular trap formation

Biochemical and Biophysical Research Communications, 2011
Neutrophil extracellular traps (NETs) that bind invading microbes are pivotal for innate host defense. There is a growing body of evidence for the significance of NETs in the pathogenesis of infectious and inflammatory diseases, but the mechanism of NET formation remains unclear. Previous observation in neutrophils of chronic granulomatous disease (CGD)
Yoko, Nishinaka, Toshiyuki, Arai, Souichi, Adachi, Akifumi, Takaori-Kondo, Kouhei, Yamashita   +4 more
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Tetrahydroisoquinolines: New Inhibitors of Neutrophil Extracellular Trap (NET) Formation

ChemBioChem, 2017
AbstractNeutrophils are short‐lived leukocytes that migrate to sites of infection as part of the acute immune response, where they phagocytose, degranulate, and form neutrophil extracellular traps (NETs). During NET formation, the nuclear lobules of neutrophils disappear and the chromatin expands and, accessorized with neutrophilic granule proteins, is
Martinez, N., Zimmermann, T., Goosmann, C., Alexander, T., Hedberg, C., Ziegler, S., Zychlinsky, A., Waldmann, H.   +7 more
openaire   +4 more sources