Results 21 to 30 of about 19,957 (258)

Influences of chloride and hypochlorite on neutrophil extracellular trap formation. [PDF]

PLoS ONE, 2012
The release by neutrophils of DNA-based extracellular traps (NETs) is a recently recognized innate immune phenomenon that contributes significantly to control of bacterial pathogens at tissue foci of infection.
Kathryn Akong-Moore, Ohn A Chow, Maren von Köckritz-Blickwede, Victor Nizet   +3 more
doaj   +1 more source

Neutrophil extracellular trap formation in supragingival biofilms

International Journal of Medical Microbiology, 2015
Oral biofilms are the causative agents of the highly prevalent oral diseases periodontitis and caries. Additionally, the host immune response is thought to play a critical role in disease onset. Neutrophils are known to be a key host response factor to bacterial challenge on host surfaces.
Josefine, Hirschfeld, Henrik, Dommisch, Philipp, Skora, Gabor, Horvath, Eicke, Latz, Achim, Hoerauf, Tobias, Waller, Toshihisa, Kawai, Søren, Jepsen, James, Deschner, Isabelle, Bekeredjian-Ding   +10 more
openaire   +2 more sources

Formation of Neutrophil Extracellular Traps under Low Oxygen Level [PDF]

Frontiers in Immunology, 2016
Since their discovery, neutrophil extracellular traps (NETs) have been characterized as a fundamental host innate immune defense mechanism. Conversely, excessive NET-release may have a variety of detrimental consequences for the host. A fine balance between NET formation and elimination is necessary to sustain a protective effect during an infectious ...
Katja Branitzki-Heinemann, Helene Möllerherm, Lena Völlger, Diab Hussein, Nicole de Buhr, Nicole de Buhr, Stefanie Blodkamp, Friederike Reuner, Graham Brogden, Hassan Y. Naim, Maren Von Köckritz-Blickwede, Maren Von Köckritz-Blickwede   +11 more
openaire   +3 more sources

Neutrophil extracellular trap formation is regulated by CXCR2 in COPD neutrophils [PDF]

European Respiratory Journal, 2018
CXCR2 might have a crucial role in neutrophil extracellular trap formation in COPD neutrophilshttp://ow.ly ...
Frauke Pedersen, Benjamin Waschki, Sebastian Marwitz, Torsten Goldmann, Anne Kirsten, Anna Malmgren, Klaus F. Rabe, Mohib Uddin, Henrik Watz   +8 more
openaire   +2 more sources

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps [PDF]

Journal of Cell Biology, 2010
Neutrophils release decondensed chromatin termed neutrophil extracellular traps (NETs) to trap and kill pathogens extracellularly. Reactive oxygen species are required to initiate NET formation but the downstream molecular mechanism is unknown. We show that upon activation, neutrophil elastase (NE) escapes from azurophilic granules and translocates to ...
Papayannopoulos, V., Metzler, K., Hakkim, A., Zychlinsky, A.   +3 more
openaire   +3 more sources

Neutrophil extracellular trap formation during surgical procedures: a pilot study

Scientific Reports, 2023
Neutrophils can release neutrophil extracellular traps (NETs) containing DNA fibres and antimicrobial peptides to immobilize invading pathogens. NET formation (NETosis) plays a vital role in inflammation and immune responses.
Melody Ying-Yu Huang, Christoph Lippuner, Marcel Schiff, Malte Book, Frank Stueber   +4 more
doaj   +1 more source

Neutrophil extracellular traps (NETs) - formation and implications.

Acta Biochimica Polonica, 2013
Neutrophils are cells of the immune system which freely circulate in blood vessels and are recruited to the inflammation sites when the human organism responds to microbial infections. One of the mechanisms of neutrophil action is the formation of neutrophil extracellular traps (NETs) The process of NET generation, called netosis, is a specific type of
Zawrotniak, Marcin, Rąpała-Kozik, Maria   +1 more
openaire   +4 more sources

Neutrophil activation and neutrophil derived neutrophil extracellular trap formation in patients with coronary artery ectasia

BMC Cardiovascular Disorders, 2020
Background This study investigated neutrophil activation and neutrophil-derived extracellular traps formation in coronary artery ectasia. Methods We enrolled 90 patients who underwent coronary angiography, and included 30 patients with coronary artery ...
Yuchao Guo, Ruifeng Liu, Lianfeng Chen, Wei Wu, Shuyang Zhang   +4 more
doaj   +1 more source

Lysophosphatidylcholine Alleviates Acute Lung Injury by Regulating Neutrophil Motility and Neutrophil Extracellular Trap Formation

Frontiers in Cell and Developmental Biology, 2022
Sepsis is predominantly initiated by bacterial infection and can cause systemic inflammation, which frequently leads to rapid death of the patient. However, this acute systemic inflammatory response requires further investigation from the perspectives of
Soi Jeong, Soi Jeong, Bora Kim, Da Jeong Byun, Da Jeong Byun, Sunmin Jin, Bo Seung Seo, Mi Hwa Shin, Ah Young Leem, Jai Jun Choung, Moo Suk Park, Young-Min Hyun, Young-Min Hyun   +12 more
doaj   +1 more source

2-Chlorofatty acids: lipid mediators of neutrophil extracellular trap formation

Journal of Lipid Research, 2018
Neutrophils form neutrophil extracellular traps (NETs), which have been implicated in microcirculatory plugging. NET formation (NETosis) involves the fusion of granule and nuclear contents, which are then released in the extracellular space ...
ElisaN.D. Palladino, Lalage A. Katunga, Grant R. Kolar, David A. Ford   +3 more
doaj   +1 more source