Results 31 to 40 of about 36,600 (202)

SPARC is a new myeloid-derived suppressor cell marker licensing suppressive activities [PDF]

, 2019
Myeloid-derived suppressor cells (MDSC) are well-known key negative regulators of the immune response during tumor growth, however scattered is the knowledge of their capacity to influence and adapt to the different tumor microenvironments and of the ...
Botti L., Cappetti B., Chiodoni C., Colombo M. P., Consonni F. M., Gulino A., Nicola M. D., Portararo P., Randon G., Sangaletti S., Sica A., Talarico G., Tripodo C.   +12 more
core   +3 more sources

Neutrophil extracellular trap formation is regulated by CXCR2 in COPD neutrophils [PDF]

European Respiratory Journal, 2018
CXCR2 might have a crucial role in neutrophil extracellular trap formation in COPD neutrophilshttp://ow.ly ...
Frauke Pedersen, Benjamin Waschki, Sebastian Marwitz, Torsten Goldmann, Anne Kirsten, Anna Malmgren, Klaus F. Rabe, Mohib Uddin, Henrik Watz   +8 more
openaire   +2 more sources

Novel insights into host-fungal pathogen interactions derived from live-cell imaging [PDF]

, 2015
Acknowledgments The authors acknowledge funding from the Wellcome Trust (080088, 086827, 075470 and 099215) including a Wellcome Trust Strategic Award for Medical Mycology and Fungal Immunology 097377 and FP7-2007–2013 grant agreement HEALTH-F2-2010 ...
A Casadevall, AK Neumann, B Amulic, B Enjalbert, B Hube, BN Gantner, C Jiménez-López, C Sasse, C Tokarski, CC Sheth, CF Urban, CGJ McKenzie, CJ Chrisman, D Armstrong-James, D Ermert, D Liebl, D Vijayan, DA Silva da, DC Savage, DJ Krysan, E Moreno-Ruiz, EK Szabo, FM Rudkin, G Chamilos, G Vande Velde, GD Brown, GD Brown, H Ma, H Ma, I Rubin-Bejerano, IE Frohner, J Behnsen, J Chandra, J Maertens, J Perlroth, J Voigt, JM Bain, JM Tam, Judith Bain, K Konig, K Schäfer, K Seider, KM Brothers, L Romani, L Romani, Lars-Peter Erwig, LE Lewis, LE Lewis, LG Tilney, LY Ngo, M Alvarez, MC Lorenz, MG Netea, MJ Patterson, MS Lionakis, MS Lionakis, N Papon, NAR Gow, Neil A. R. Gow, O Uzun, O Zaragoza, P Martino, P Miramón, Q Qian, R García-Rodas, RA Drummond, RD Diamond, RI Lehrer, S Bruns, S El-Kirat-Chatel, S Keppler-Ross, S Mitra, SA Johnston, SC Cheng, SE Heinsbroek, V Aimanianda, Wellington, Y Luo   +77 more
core   +1 more source

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps [PDF]

Journal of Cell Biology, 2010
Neutrophils release decondensed chromatin termed neutrophil extracellular traps (NETs) to trap and kill pathogens extracellularly. Reactive oxygen species are required to initiate NET formation but the downstream molecular mechanism is unknown. We show that upon activation, neutrophil elastase (NE) escapes from azurophilic granules and translocates to ...
Papayannopoulos, V., Metzler, K., Hakkim, A., Zychlinsky, A.   +3 more
openaire   +3 more sources

Neutrophil extracellular trap formation during surgical procedures: a pilot study

Scientific Reports, 2023
Neutrophils can release neutrophil extracellular traps (NETs) containing DNA fibres and antimicrobial peptides to immobilize invading pathogens. NET formation (NETosis) plays a vital role in inflammation and immune responses.
Melody Ying-Yu Huang, Christoph Lippuner, Marcel Schiff, Malte Book, Frank Stueber   +4 more
doaj   +1 more source

Platelets: New bricks in the building of neutrophil extracellular traps [PDF]

, 2016
In addition to being key elements in hemostasis and thrombosis, platelets have an important role in the inflammatory and innate immune response. This activity is associated with their capability to recognize pathogens through the expression of toll-like ...
Carestia, Agostina, Kaufman, Tomás, Schattner, Mirta Ana   +2 more
core   +1 more source

In vitro induction of NETosis: Comprehensive live imaging comparison and systematic review [PDF]

, 2017
__Background__ Multiple inducers of in vitro Neutrophil Extracellular Trap (NET) formation (NETosis) have been described. Since there is much variation in study design and results, our aim was to create a systematic review of NETosis inducers and perform
Abraham, T.E. (Tsion), Autar, A. (Anouchska), Beusekom, H.M.M. (Heleen) van, Cappellen, W.A. (Gert) van, Hoppenbrouwers, T. (Tamara), Houtsmuller, A.B. (Adriaan), Maat, M.P.M. (Moniek) de, Neck, J.W. (Han) van, Sultan, A.R. (Andi R.), Wamel, W.J.B. (Willem) van   +9 more
core   +1 more source

Lysophosphatidylcholine Alleviates Acute Lung Injury by Regulating Neutrophil Motility and Neutrophil Extracellular Trap Formation

Frontiers in Cell and Developmental Biology, 2022
Sepsis is predominantly initiated by bacterial infection and can cause systemic inflammation, which frequently leads to rapid death of the patient. However, this acute systemic inflammatory response requires further investigation from the perspectives of
Soi Jeong, Soi Jeong, Bora Kim, Da Jeong Byun, Da Jeong Byun, Sunmin Jin, Bo Seung Seo, Mi Hwa Shin, Ah Young Leem, Jai Jun Choung, Moo Suk Park, Young-Min Hyun, Young-Min Hyun   +12 more
doaj   +1 more source

Vav1 inhibits RANKL-induced osteoclast differentiation and bone resorption [PDF]

, 2019
Vav1 is a Rho/Rac guanine nucleotide exchange factor primarily expressed in hematopoietic cells. In this study, we investigated the potential role of Vav1 in osteoclast (OC) differentiation by comparing the ability of bone marrow mononuclear cells (BMMCs)
Cha, Young-Nam, Dinauer, Mary C., Jang, Jin Sun, Kang, In Soon, Kim, Chaekyun, Kim, Young-June, Lee, Zang Hee   +6 more
core   +2 more sources

Neutrophil activation and neutrophil derived neutrophil extracellular trap formation in patients with coronary artery ectasia

BMC Cardiovascular Disorders, 2020
Background This study investigated neutrophil activation and neutrophil-derived extracellular traps formation in coronary artery ectasia. Methods We enrolled 90 patients who underwent coronary angiography, and included 30 patients with coronary artery ...
Yuchao Guo, Ruifeng Liu, Lianfeng Chen, Wei Wu, Shuyang Zhang   +4 more
doaj   +1 more source