Results 271 to 280 of about 75,140 (320)

Antineutrophil Cytoplasmic Antibodies Contribute to Airway Inflammation via Induction of Neutrophil Extracellular Traps in Children With Bronchiolitis Obliterans. [PDF]

Clin Respir J
Chen X, Wu S, Liu Z, Huang Z, Xu J, Wu Z, Li H, Li H, Chen D.   +8 more
europepmc   +1 more source

Nanomedicine Meets Immunotherapy: Transforming Chimeric Antigen Receptor T Cell Treatment for Solid Tumors

Small Science, EarlyView.
This review highlights recent advances in nanomedicine that enhance chimeric antigen receptor (CAR) T cell therapy against solid tumors. It discusses key barriers to CAR T cell efficacy and outlines nanotechnology‐based strategies to improve tumor targeting, remodel the immunosuppressive microenvironment, and integrate nanomaterials into CAR T cell ...
Stephen O’Rourke, Nuo Xu, Hongjun Wang, Hexin Chen   +3 more
wiley   +1 more source

Neutrophil Extracellular Traps Activate Meningeal Fibroblast to Aggravate Subarachnoid Fibrosis in Kaolin-Induced Hydrocephalus in Rats. [PDF]

Immun Inflamm Dis
Ma C, Feng Z, Xiong B, Liang L, Liu S, Min L, Zhang Q, Guo P, Chen J, Tan L, Hou J, Chen Z.   +11 more
europepmc   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Low-density granulocytes and neutrophil extracellular traps in dengue, impacts of interferon alpha and cell-free DNA. [PDF]

Sci Rep
Saisorn W, Phuengmaung P, Kaewduangduen W, Bhunyakarnjanarat T, Doi K, Chancharoenthana W, Leelahavanichkul A.   +6 more
europepmc   +1 more source

The Impact of Environmental Pollution and Climate Change on Allergic Rhinitis and Lung Diseases

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Environmental pollution and climate change seriously affect human health, leading to the onset and exacerbation of chronic respiratory diseases, such as allergic rhinitis and lung diseases. Over the past several decades, increasing air pollution and environmental exposure owing to global urbanization, industrialization, and rapid economic ...
Xin‐Yan Liu, Rui‐Ming Han, Yong‐Tai Wang, Dong‐Dong Zhu, Cui‐Da Meng   +4 more
wiley   +1 more source

Neutrophil extracellular traps in ischemic stroke: mechanisms, clinical implications, and therapeutic potential. [PDF]

Front Neurol
He W, Wu Z, Liu Y, Ye Z.
europepmc   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Neutrophil extracellular traps regulate LDHA expression to promote colorectal cancer liver metastasis. [PDF]

J Transl Med
Li N, Yang S, Hu C, Zheng J, Yang H, Jiang T, Li X, Han Q, Zhang X, Yang Y, Khan S, Sun B.   +11 more
europepmc   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source