Results 171 to 180 of about 845,167 (291)

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

Medicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo, Kaeun Chae, Jueun Lee, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Simplified flow cytometric quantification of human neutrophil extracellular traps (NETs). [PDF]

J Inflamm (Lond)
Rinaldi G, Cheng KKW, McCann C, Rossi F, Rodriguez-Rios M, Dhaliwal K, Bebes A, Duncan L, Yuecel R, Rossi AG, Robb CT.   +10 more
europepmc   +1 more source

The central role of neutrophil extracellular traps (NETs) and by-products in COVID-19 related pulmonary thrombosis. [PDF]

Immun Inflamm Dis, 2023
Li S, Wang H, Shao Q.
europepmc   +1 more source

Molecular Biomarkers in Meniere's Disease: A Scoping Review of Current Evidence

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Meniere's disease is a complex chronic inner ear condition that is characterized by vertigo, tinnitus, aural fullness, and progressive hearing loss. Currently, diagnostic strategies remain symptom‐driven, and treatments focus on management of discrete episodes rather than targeting underlying pathophysiology.
Hamza Kamran, Zaharadeen Jimoh, Tariq Issa, Nahla A. Gomaa   +3 more
wiley   +1 more source

Development of a Predictive Model for Transfusion-Related Acute Lung Injury Based on Neutrophil Extracellular Traps (NETs). [PDF]

Mediators Inflamm
Wang Q, Li Z, Shao J, Qiang X, Gong W, Sun L, Yang H, Li Z, Wang J.   +8 more
europepmc   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

PROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima, Wilson Dias Segura, Leonardo Brogliato de Moraes, Reinaldo Souza Oliveira, Pedro Henrique Corteletti Manfio, Alison Felipe Alencar Chaves, Wagner Luiz Batista   +6 more
wiley   +1 more source

Inflammasome Activation by Neutrophil Extracellular Traps (NETs) in the MDA-MB-231 Human Breast Cancer Cell Line. [PDF]

Int J Mol Sci
Silva AGD, Pereira E, Almeida VH, Pinto LD, Souza JL, Tilli TM, Coutinho-Silva R, Medei E, Konig S, Monteiro RQ.   +9 more
europepmc   +1 more source

Proteomic Analysis of Mixed Cell Membrane Extracts From Triple‐Negative Breast Cancer Cell Lines Revealed Broad Metabolic Reprogramming Associated With Tumor Progression

PROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca, Violeta Larios‐Serrato, María Luisa Labra‐Barrios, Emmanuel Ríos‐Castro, Carlos Alberto Castañón‐Sánchez, Rodolfo Moreno‐Castillo, Erika Beatriz Ángeles‐Morales, Juan Pedro Luna‐Arias   +7 more
wiley   +1 more source

Neutrophil Extracellular Traps in Tumors and Potential Use of Traditional Herbal Medicine Formulations for Its Regulation

International Journal of Nanomedicine
Xiang Li,1,* Lei Hu,1,* Abid Naeem,2,3,* Shanghua Xiao,2 Ming Yang,2 Hongming Shang,4 Jing Zhang1,2 1National Pharmaceutical Engineering Center for Solid Preparation in Chinese Herbal Medicine, Jiangxi University of Chinese Medicine, Nanchang,
Li X, Hu L, Naeem A, Xiao S, Yang M, Shang H, Zhang J   +6 more
doaj  

Presence of neutrophil extracellular traps (NETs) in different types of human urinary tract infections (UTI). A pilot study. [PDF]

Front Immunol
Schröder Alvarez L, Conejeros I, Espinosa G, Salinas-Varas C, Ott B, Weigel M, Imirzalioglu C, Fritzenwanker M, Windhorst AC, Hain T, Taubert A, Hermosilla C, Wagenlehner F.   +12 more
europepmc   +1 more source