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Effects of bromelain, melatonin, and thymoquinone on neutrophil extracellular trap formation and macrophage polarization in experimental periodontitis [PDF]
Journal of Applied Oral SciencePeriodontitis is a chronic inflammatory disease characterized by dysregulated immune responses leading to alveolar bone loss. Formation of neutrophil extracellular traps and macrophage polarization play critical roles in its pathogenesis, and natural ...
Şükran Acipinar +3 more
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Impaired neutrophil extracellular trap formation in β-thalassaemia/HbE
Scientific Reports, 2022 Neutrophil dysfunction contributes to a high susceptibility to severe bacterial infection which is a leading cause of morbidity and mortality in β-thalassaemia/HbE, especially in splenectomised patients.
Rattanawan Thubthed +7 more
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Aggregatibacter actinomycetemcomitans NadN contributes to neutrophil extracellular trap degradation [PDF]
Journal of Oral MicrobiologyBackground Neutrophils Extracellular Traps (NET) immobilize and kill extracellular pathogens. Aggregatibacter actinomycetemcomitans (Aa), associated with aggressive forms of periodontitis, has been shown to induce NET release. However, it remains unknown
Yaowapa Puanglai +5 more
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Hypervirulent Klebsiella pneumoniae induces liver abscess by promoting neutrophil extracellular trap formation through NLRP3 inflammasome activation [PDF]
Microbiology SpectrumHypervirulent Klebsiella pneumoniae (hvKP) has spread globally, causing severe liver abscesses. Neutrophil extracellular trap formation (NETosis) is an essential defense mechanism of neutrophils. However, the role of pathogenicity and molecular mechanism
Qian Ou +13 more
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Neutrophil Extracellular Trap-Driven Occlusive Diseases
Cells, 2021 The enlightenment of the formation of neutrophil extracellular traps (NETs) as a part of the innate immune system shed new insights into the pathologies of various diseases. The initial idea that NETs are a pivotal defense structure was gradually amended
Kursat Oguz Yaykasli +6 more
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NETome: A model to Decode the Human Genome and Proteome of Neutrophil Extracellular Traps
Scientific Data, 2022 Measurement(s) Genome Sequence Reads • Protein Abundance Technology Type(s) Illuminia • liquid chromatography-tandem mass spectrometry Factor Type(s) Neutrophil extracellular trap genome sequence • Neutrophil extracellular trap protein abundance Sample ...
David Scieszka +5 more
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Mediators of Inflammation, 2020 Ischemia reperfusion (IR) can lead to acute kidney injury and can be complicated by acute lung injury, which is one of the leading causes of acute kidney injury-related death.
Mingjun Du +5 more
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Gels, 2023 Ocular alkali burns recruit neutrophils and triggers neutrophil extracellular trap (NET)-neovascularization cascade effects that limit ocular surface reconstruction and functional repair.
Jun Zhang +4 more
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Mast Cell Tryptase Potentiates Neutrophil Extracellular Trap Formation
Journal of Innate Immunity, 2021 Previous research has indicated an intimate functional communication between mast cells (MCs) and neutrophils during inflammatory conditions, but the nature of such communication is not fully understood.
Gunnar Pejler +6 more
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Frontiers in Immunology, 2016 In this study we identified and characterized the potential of a high ratio of bicarbonate to CO2 and a moderately alkaline pH to render neutrophils prone to undergo neutrophil extracellular trap (NET) formation.
Christian Maueröder +14 more
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