Results 21 to 30 of about 847,167 (258)

Histone Acetylation Promotes Neutrophil Extracellular Trap Formation

Biomolecules, 2019
Neutrophils undergo a unique form of cell death to generate neutrophil extracellular traps (NETs). It is well established that citrullination of histones (e.g., CitH3) facilitates chromatin decondensation during NET formation (NETosis), particularly ...
Hussein J. Hamam, Meraj A. Khan, Nades Palaniyar   +2 more
doaj   +1 more source

The Role of Neutrophil Extracellular Traps in Cancer

Frontiers in Oncology, 2021
Neutrophils are vital components of innate and adaptive immunity. It is widely acknowledged that in various pathological conditions, neutrophils are activated and release condensed DNA strands, triggering the formation of neutrophil extracellular traps ...
Bo-Zong Shao, Yi Yao, Jin-Ping Li, Ning-Li Chai, En-Qiang Linghu   +4 more
doaj   +1 more source

Molecular mechanisms and therapeutic target of NETosis in diseases

MedComm, 2022
Evidence shows that neutrophils can protect the host against pathogens in multiple ways, including the formation and release of neutrophil extracellular traps (NETs).
Jiayu Huang, Weiqi Hong, Meihua Wan, Limin Zheng   +3 more
doaj   +1 more source

Top significantly differentially expressed up- and downregulated genes of interest in the “Neutrophil Extracellular Trap Formation” KEGG pathway, at 6hr of Mtb infection between PMN_HITTIN and PMN_HIT.

, 2023
Top significantly differentially expressed up- and downregulated genes of interest in the “Neutrophil Extracellular Trap Formation” KEGG pathway, at 6hr of Mtb infection between PMNHITTIN and PMNHIT.
Craig J. Kinnear (6241367), Eileen G. Hoal (8940992), Erwin Schurr (238686), Pauline Cassart (3481769), Naomi Okugbeni (16877804), Rachel Evans (5473385), Allison Seeger (9639860), Anna K. Coussens (16877810), Jurgen A. Kriel (16877801), Lize Engelbrecht (16877798), Robert J. Wilkinson (7724204), Elouise E. Kroon (16877795), Marianna Orlova (238676), Ben Loos (590100), Gerard C. Tromp (16877807), Marlo Möller (458883), Wilian Correa-Macedo (11813183)   +16 more
core   +1 more source

Neutrophil extracellular trap formation is elicited in response to cold physical plasma [PDF]

, 2016
Cold physical plasma is an ionized gas with a multitude of components, including hydrogen peroxide and other reactive oxygen and nitrogen species. Recent studies suggest that exposure of wounds to cold plasma may accelerate healing.
Hasse, Sybille, Bekeschus, Sander, Masur, Kai, Kolata, Julia, Winterbourn, VChristine C., Parker, Heather A., Bröker, Barbara M.   +6 more
core   +1 more source

Chromatin swelling drives neutrophil extracellular trap release

Nature Communications, 2018
Neutrophilic granulocytes release their own DNA (NETosis) as neutrophil extracellular traps to capture pathogens. Here, the authors use time-resolved fluorescence and atomic force microscopy and reveal that NETosis is highly organized into three distinct
Elsa Neubert, Daniel Meyer, Francesco Rocca, Gökhan Günay, Anja Kwaczala-Tessmann, Julia Grandke, Susanne Senger-Sander, Claudia Geisler, Alexander Egner, Michael P. Schön, Luise Erpenbeck, Sebastian Kruss   +11 more
doaj   +1 more source

Nucleosomes and neutrophil activation in sickle cell disease painful crisis

Haematologica, 2013
Activated polymorphonuclear neutrophils play an important role in the pathogenesis of vaso-occlusive painful sickle cell crisis. Upon activation, polymorphonuclear neutrophils can form neutrophil extracellular traps.
Marein Schimmel, Erfan Nur, Bart J. Biemond, Gerard J. van Mierlo, Shabnam Solati, Dees P. Brandjes, Hans-Martin Otten, John-John Schnog, Sacha Zeerleder   +8 more
doaj   +1 more source

Supplemental Material - Liver proteomic analysis reveals acute liver failure induced by lipopolysaccharide/D-galactosamine in rats involved in neutrophil extracellular trap formation

, 2022
Supplemental Material for Liver proteomic analysis reveals acute liver failure induced by lipopolysaccharide/D-galactosamine in rats involved in neutrophil extracellular trap formation by Keyin Wang, Zhuolin Zou, Ting Zou, Dahai Wei and Min Deng in ...
Min Deng (114029), Keyin Wang (12916023), Ting Zou (331327), Dahai Wei (1392451), Zhuolin Zou (12916026)   +4 more
core   +1 more source

MOESM1 of Superoxide induces Neutrophil Extracellular Trap Formation in a TLR-4 and NOX-Dependent Mechanism

, 2018
Superoxide Induces Neutrophil Extracellular Trap Formation in a TLR-4 and NOX-Dependent ...
Ahmed Al-Khafaji (5817152), Hamza Yazdani (5817158), Hai Huang (140371), Samer Tohme (5817155), Allan Tsung (572167), David Miller (62440)   +5 more
core   +1 more source

The net effect of ANCA on neutrophil extracellular trap formation

, 2018
The formation of neutrophil extracellular traps induced by antineutrophil cytoplasmic autoantibodies has been implicated in the pathogenesis of antineutrophil cytoplasmic autoantibody-associated vasculitis. Kraaij et al.
Abraham Rutgers, Kallenberg, Cees G M, Heeringa, Peter; id_orcid, Rutgers, Abraham; id_orcid, Peter Heeringa, Cees G.M. Kallenberg   +5 more
core   +1 more source