Results 41 to 50 of about 847,167 (258)

Particles of different sizes and shapes induce neutrophil necroptosis followed by the release of neutrophil extracellular trap-like chromatin [PDF]

, 2017
The human body is exposed to a wide range of particles of industrial, environmental or internal origin such as asbestos, alum, silica or crystals of urate, calcium phosphate, calcium oxalate, cystine or cholesterol. Phagocytic clearance of such particles
Foresto-Neto, Orestes, Nakazawa, Daigo, Honarpisheh, Mohsen, Stefanie Steiger, Jyaysi Desai, Boor, Peter, Shrikant R. Mulay, Buhl, Eva Miriam, Steiger, Stefanie, Orestes Foresto-Neto, Daigo Nakazawa, Hans-Joachim Anders, Desai, Jyaysi, Anders, Hans-Joachim, Mulay, Shrikant R., Bastian Popper, Popper, Bastian, Mohsen Honarpisheh, Eva Miriam Buhl, Peter Boor   +19 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Neutrophil metabolomics in severe COVID-19 reveal GAPDH as a suppressor of neutrophil extracellular trap formation

, 2023
Severe COVID-19 is characterized by an increase in the number and changes in the function of innate immune cells including neutrophils. However, it is not known how the metabolome of immune cells changes in patients with COVID-19.
Xue Xiao, Marcel Mettlen, Yafeng Li, Jessica G. Moreland, Jessica S. Hook, Stephen S. Chung, Lin Xu, Qing Ding, Michalis Agathocleous   +8 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

INI889392 Supplemetal Material - Supplemental material for Periodontal therapy increases neutrophil extracellular trap degradation

, 2019
Supplemental material, INI889392 Supplemetal Material for Periodontal therapy increases neutrophil extracellular trap degradation by Carolyn GJ Moonen, Kirsten GD Buurma, Mouri RJ Faruque, Maria G Balta, Erol Liefferink, Sergio Bizzarro, Elena A Nicu and
Elena A Nicu (8026598), Kirsten GD Buurma (8026586), Maria G Balta (8026592), Carolyn GJ Moonen (8026583), Mouri RJ Faruque (8026589), Erol Liefferink (8026595), Bruno G Loos (8026601), Sergio Bizzarro (792910)   +7 more
core   +1 more source

Cigarette smoke modifies neutrophil chemotaxis, neutrophil extracellular trap formation and inflammatory response‐related gene expression [PDF]

, 2018
Background and ObjectiveCigarette smoking is a major risk factor for periodontitis, and smoking perturbs neutrophil reactive oxygen species production.
White, Phillipa, Chapple, Iain; id_orcid, H. J. Wright, P. R. Cooper, J. B. Matthews, Milward, M. R., P. C. White, I. L.C. Chapple, Wright, H. J., Matthews, J. B., Cooper, P. R., J. Hirschfeld, M. R. Milward, Hirschfeld, J.; id_orcid   +13 more
core   +1 more source

The emerging role of neutrophil extracellular traps in fungal infection

Frontiers in Cellular and Infection Microbiology, 2022
Fungal infections are global public health problems and can lead to substantial human morbidity and mortality. Current antifungal therapy is not satisfactory, especially for invasive, life-threatening fungal infections. Modulating the antifungal capacity
Chuting Liang, Ni Lian, Min Li, Min Li
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

T Cell–Independent Mechanisms Associated with Neutrophil Extracellular Trap Formation and Selective Autophagy in IL-17A–Mediated Epidermal Hyperplasia [PDF]

, 2016
IL-17A has been strongly associated with epidermal hyperplasia in many cutaneous disorders. However, because IL-17A is mainly produced by αβ and γδT cells in response to IL-23, the role of T cells and IL-23 has overshadowed any IL-17A-independent actions.
Kuchroo, Vijay K, Maverakis, Emanual, Adamopoulos, Iannis E, Nestle, Frank O, Suzuki, Erika, Bouchareychas, Laura, Sarin, Ritu   +6 more
core   +1 more source

Cross-sectional study of proteomic differences between moderate and severe psoriasis

Scientific Reports
Although an ongoing understanding of psoriasis vulgaris (PV) pathogenesis, little is known about the proteomic differences between moderate and severe psoriasis.
Lingling Wu, Chen Cen, Bibo Xie, Lihua Hu, Jia Huang, Ningning Shen, Qiang Dong   +6 more
doaj   +1 more source