Results 241 to 250 of about 194,382 (299)

Icaritin inhibits the progression of urothelial cancer by suppressing PADI2-mediated neutrophil infiltration and neutrophil extracellular trap formation. [PDF]

Acta Pharm Sin B
Mou Z, Chen Y, Hu J, Hu Y, Zou L, Chen X, Liu S, Yin Q, Gong J, Li S, Mao S, Xu C, Jiang H.   +12 more
europepmc   +1 more source

Neutrophil‐Driven Cascade‐Targeted Nanocarriers Restore Mitochondrial Homeostasis to Ameliorate Renal Ischemia–Reperfusion Injury

Advanced Science, EarlyView.
A neutrophil‐mediated dual‐targeting liposome (NKN‐LNP) is developed to treat renal ischemia–reperfusion injury. The system enables spatiotemporally controlled delivery of NMN to injured tubules via MMP‐2/9 activation and KIM1 recognition, restoring mitochondrial function through NAD+‐SIRT3 signaling and preventing the transition from acute kidney ...
Hangbin Ma, Yang Li, Shen Lin, Feifan Chu, Gaozhan Ren, Yinhui Mao, Mingzhi Wu, Yuning Ma, Qiwei Ji, Zujie Chen, Jinzhong Ji, Mingxin Sun, Yongpeng Xu, Xiaoli Sun, Longguang Tang, Hao Zhou   +15 more
wiley   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

Blocking the TRAIL-DR5 Pathway Reduces Cardiac Ischemia-Reperfusion Injury by Decreasing Neutrophil Infiltration and Neutrophil Extracellular Traps Formation. [PDF]

Cardiovasc Drugs Ther
Wang X, Xie R, Zhao D, Wang G, Zhang L, Shi W, Chen Y, Mo T, Du Y, Tian X, Wang W, Cao R, Ma Y, Wei Y, Wang Y.   +14 more
europepmc   +1 more source

TRIM26 alleviates fatal immunopathology by regulating inflammatory neutrophil infiltration during Candida infection. [PDF]

PLoS Pathog
Zhao G, Li Y, Chen T, Liu F, Zheng Y, Liu B, Zhao W, Qi X, Sun W, Gao C.   +9 more
europepmc   +1 more source

Synergistic potentiation of the anti-metastatic effect of a Ginseng-Salvia miltiorrhiza herbal pair and its biological ingredients via the suppression of CD62E-dependent neutrophil infiltration and NETformation. [PDF]

J Adv Res
Lu K, Xia Y, Cheng P, Li Y, He L, Tao L, Wei Z, Lu Y.   +7 more
europepmc   +1 more source

Reduced Monocyte and Neutrophil Infiltration and Activation by P-Selectin/CD62P Inhibition Enhances Thrombus Resolution in Mice. [PDF]

Arterioscler Thromb Vasc Biol
Kral-Pointner JB, Haider P, Szabo PL, Salzmann M, Brekalo M, Schneider KH, Schrottmaier WC, Kaun C, Bleichert S, Kiss A, Sickha R, Hengstenberg C, Huber K, Brostjan C, Bergmeister H, Assinger A, Podesser BK, Wojta J, Hohensinner P.   +18 more
europepmc   +1 more source

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Subcutaneous Neutrophilic Infiltrates in Acute Febrile Neutrophilic Dermatosis

Archives of Dermatology, 1983
• A patient had an evolving hematologic disorder, accompanied by tender, red, subcutaneous nodules. Histologically, there were dense neutrophilic infiltrates confined to the subcutaneous adipose tissue. Three months later, a typical episode of acute febrile neutrophilic dermatosis (ND) developed in the patient, and she was found to have acute myeloid ...
P H, Cooper, H F, Frierson, K E, Greer
openaire   +3 more sources

Neutrophil infiltration into human gliomas

Acta Neuropathologica, 1999
Human gliomas were analysed for the infiltration of neutrophils using immunohistochemistry by staining sections for CD15-positive and myeloperoxidase-positive cells. Over 70% of all glioma samples analysed (n = 105) had significant neutrophil infiltration, but there was a marked and significant correlation between tumour grade and the extent of the ...
RICEVUTI, GIOVANNI, Fossati G, Edwards Sw, Walker C, Dalton A, Rossi Ml   +5 more
openaire   +2 more sources