Results 21 to 30 of about 194,382 (299)

Possible anti-inflammatory role of Zingiberis processum rhizoma, one component of the Kampo formula daikenchuto, against neutrophil infiltration through muscarinic acetylcholine receptor activation

Journal of Pharmacological Sciences, 2018
Zingiberis processum rhizoma (ZPR) is a major active component of daikenchuto (DKT), which induces anti-inflammatory action by inhibiting macrophage infiltration. However, it is unclear whether ZPR is related to DKT-induced anti-inflammatory action via a
Mari Endo, Masatoshi Hori, Hiroshi Ozaki, Tetsuro Oikawa, Hiroshi Odaguchi, Toshihiko Hanawa   +5 more
doaj   +1 more source

Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis. [PDF]

, 2019
Chronic itch remains a highly prevalent disorder with limited treatment options. Most chronic itch diseases are thought to be driven by both the nervous and immune systems, but the fundamental molecular and cellular interactions that trigger the ...
Barton, Gregory M, Bautista, Diana M, Brem, Rachel B, Brock, Emily C, Deguine, Jacques, Gronert, Karsten, Hill, Rose Z, Kucirek, Natalie, Rifi, Ziad, Schwendinger-Schreck, Jamie, Walsh, Carolyn M, Wei, Jessica   +11 more
core   +1 more source

Myrtucommulone from Myrtus communis exhibits potent anti-inflammatory effectiveness in vivo. [PDF]

, 2009
Myrtucommulone a nonprenylated acylphloroglucinol contained in the leaves of myrtle (Myrtus communis), has been reported to suppress the biosynthesis of eicosanoids by inhibition of 5-lipoxygenase and cyclooxygenase-1 in vitro and to inhibit the release ...
BRAMANTI P., CAMINITI R., CUZZOCREA S., DI PAOLA R., GENOVESE T., KOEBERLE A., MAZZON E., PERGOLA C., ROSSI, ANTONIETTA, SAUTEBIN, LIDIA, WERZ O.   +10 more
core   +1 more source

Formylpeptide receptors mediate rapid neutrophil mobilization to accelerate wound healing.

PLoS ONE, 2014
Wound healing is a multi-phased pathophysiological process requiring chemoattractant receptor-dependent accumulation of myeloid cells in the lesion. Two G protein-coupled formylpeptide receptors Fpr1 and Fpr2 mediate rapid neutrophil infiltration in the ...
Mingyong Liu, Keqiang Chen, Teizo Yoshimura, Ying Liu, Wanghua Gong, Yingying Le, Ji-Liang Gao, Jianhua Zhao, Ji Ming Wang, Aimin Wang   +9 more
doaj   +1 more source

Xanthine oxidase and neutrophil infiltration in intestinal ischemia [PDF]

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1986
A growing body of experimental data indicates that reactive oxygen metabolites such as superoxide, hydrogen peroxide, and hydroxyl radical may mediate the mucosal injury produced by reperfusion of ischemic intestine. Xanthine oxidase has been proposed as the primary source of these reduced O2 species because pretreatment with xanthine oxidase ...
M B, Grisham, L A, Hernandez, D N, Granger   +2 more
openaire   +2 more sources

Involvement of leukotriene pathway in the pathogenesis of ischemia-reperfusion injury and septic and non-septic shock. [PDF]

, 2009
The 5-lipoxygenase (5-LO) pathway is responsible for the production of leukotrienes (LTs), inflammatory lipid mediators which play a role in innate immunity. More recently, a pivotal role of LTs in ischemia-reperfusion and shock injury has been suggested.
CUZZOCREA S, ROSSI, ANTONIETTA, SAUTEBIN, LIDIA   +2 more
core   +1 more source

Neutrophil Infiltration of Culprit Lesions in Acute Coronary Syndromes [PDF]

Circulation, 2002
Background— Neutrophils in unstable atherosclerotic lesions have not received much consideration, despite accumulating evidence suggesting a link between systemic inflammation and acute coronary syndromes.
Naruko, Takahiko, Ueda, Makiko, Haze, Kazuo, van der Wal, Allard C., van der Loos, Chris M., Itoh, Akira, Komatsu, Ryushi, Ikura, Yoshihiro, Ogami, Masayuki, Shimada, Yoshihisa, Ehara, Shoichi, Yoshiyama, Minoru, Takeuchi, Kazuhide, Yoshikawa, Junichi, Becker, Anton E.   +14 more
openaire   +3 more sources

Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury. [PDF]

, 2018
BACKGROUND: Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2.

core   +2 more sources

Pyoderma gangrenosum: problems related to the diagnostics and treatment

Vestnik Dermatologii i Venerologii, 2017
The authors provide current data related to the etiology, pathogenesis, classification, clinical picture, differential diagnostics and treatment methods of pyoderma gangrenosum.
A. V. Patrushev, A. V. Samtsov, V. V. Barbinov, A. V. Sukharev, I. E. Belousova   +4 more
doaj   +1 more source

Spectrum of Thrombotic Complications in Fatal Cases of COVID-19: Focus on Pulmonary Artery Thrombosis In Situ

Viruses, 2023
COVID-19-related thrombosis affects the venous and arterial systems. Data from 156 autopsies of COVID-19 patients were retrospectively analyzed to investigate the pattern of thrombotic complications and factors associated with pulmonary artery thrombosis
Anastasiya S. Babkina, Mikhail Y. Yadgarov, Alexey V. Volkov, Artem N. Kuzovlev, Andrey V. Grechko, Arkady M. Golubev   +5 more
doaj   +1 more source