Results 101 to 110 of about 2,507 (174)

The limitations of in vitro experimentation in understanding biofilms and chronic infection [PDF]

, 2015
We have become increasingly aware that during infection, pathogenic bacteria often grow in multi- cellular biofilms which are often highly resistant to antibacterial strategies.
Abraham, Akiyama, Aled E.L. Roberts, Alhede, Alhede, Armbruster, Banin, Barken, Bergan, Bjarnsholt, Bjarnsholt, Bjarnsholt, Bjarnsholt, Bjarnsholt, Bragonzi, Brandt, Burmølle, Campoccia, Carterson, Cash, Ceri, Chaney, Chiang, Christensen, Christensen, Chuang-Smith, Clarke, Costerton, Costerton, Costerton, Costerton, Crone, Cullen, Dai, Dalton, Darch, Das, Davis, De Beer, DeLeon, Deutschbauer, Ding, Drenkard, Elias, Engelsman, Eriksson, Fazli, Federle, Folsom, Fothergill, Fung, Fung, Goeres, Goeres, Guiton, Hall, Harrison, Homøe, Huang, Hull, Høiby, Høiby, Høiby, Jakobsen, James, Jesaitis, Johnson, Johnson, Kadurugamuwa, Kadurugamuwa, Kasper N. Kragh, Kirketerp-Møller, Klausen, Klausen, Kolenbrander, Kolpen, Korgaonkar, Kragh, Kukavica-Ibrulj, Lawrence, Lazarus, Lehnhardt, Leid, Martinez-Gutierrez, Mayer, McCoy, McNab, Monds, Mowat, Mulcahy, Murray, Murray, Nelson, Nickel, Nix, O'Neill, Palmer, Palmer, Palmer, Pamp, Pamp, Parsa, Pedersen, Percival, Peters, Pitts, Pogorelov, Prabhakara, Rendueles, Rickard, Rietsch, Rimondini, Roche, Rodríguez-Martínez, Rogers, Rogers, Rudney, Santos, Schleheck, Shrout, Sibley, Son, Sousa, Starke, Stephen P. Diggle, Sternberg, Stewart, Stewart, Stoodley, Stoodley, Sullivan, Thomas Bjarnsholt, Thomsen, Tolker-Nielsen, Tulinski, Turner, Turner, Van Gennip, Vyas, Waar, Walters, Waters, Werthén, Williams, Wolcott, Wolcott, Wright, Zelver, Zhao   +148 more
core   +2 more sources

Cunning Pathogen Tactics: Neutrophil Movement Influenced by Bacterial Attractants in the Experimental Model

Cellular Microbiology
To explore the peculiarities of neutrophil motility, two models of chemoattraction were created: a horizontal model, where a container with bacterial chemoattractant was attached laterally to the endotheliocyte monolayer, and a vertical model, simulating
Svetlana N. Pleskova, Nikolay А. Bezrukov, Ekaterina N. Gorshkova, Eseniya V. Otstavnova, Dmitry V. Novikov   +4 more
doaj   +1 more source

Albumin reprograms the B cell transcriptional landscape and improves neutrophil antimicrobial function in patients with decompensated cirrhosis

JHEP Reports
Background & Aims: Patients with acutely decompensated (AD) cirrhosis are immunocompromised and particularly susceptible to infections. This study investigated the immunomodulatory actions of albumin by which this protein may lower the incidence of ...
Joan Clària, Ferran Aguilar, Juan-José Lozano, Laura Jiménez-Gracia, Juan C. Nieto, Berta Romero-Grimaldo, Xavi Marcos-Fa, Emma Giarracco, Emmanuel Weiss, Jonel Trebicka, Inmaculada Hernàndez, Javier Fernandez, Mireia Casulleras, Cristina López-Vicario, Sinan Muldur, Alex Hopke, Alexandru Vlagea, Ana M. Aransay, Domenica Marchese, Mauro Bernardi, Rajiv Jalan, Paolo Angeli, Giuliana Magri, Andrea Cerutti, Daniel Irimia, Holger Heyn, Vicente Arroyo, Richard Moreau   +27 more
doaj   +1 more source

Biological relevance of mucoid vs. nonmucoid morphotype variation by Burkholderia cepacia complex [PDF]

, 2012
Tese de mestrado. Biologia (Biologia Celular e Biotecnologia). Universidade de Lisboa, Faculdade de Ciências, 2012O género Burkholderia é constituído por um grupo de bactérias gram-negativas que apresentam uma elevada diversidade metabólica e que podem ...
Tavares, Andreia Filipa Campos, 1989-
core  

Intelligent Leukaemia Diagnosis with Bare-Bones PSO based Feature Optimization [PDF]

, 2017
In this research, we propose an intelligent decision support system for acute lymphoblastic leukaemia (ALL) diagnosis using microscopic images. Two Bare-bones Particle Swarm Optimization (BBPSO) algorithms are proposed to identify the most significant ...
Lim, Chee Peng, Neoh, Siew Chin, Srisukkham, Worawut, Todryk, Stephen, Zhang, Li   +4 more
core   +1 more source

Resident Macrophages Cloak Tissue Microlesions to Prevent Neutrophil-Driven Inflammatory Damage

, 2019
Neutrophils are attracted to and generate dense swarms at sites of cell damage in diverse tissues, often extending the local disruption of organ architecture produced by the initial insult.
Germain, R., Lämmermann, T., Martins, A., Tsang, J., Uderhardt, S.   +4 more
core   +1 more source

Effects of the PI3K pathway on neutrophil chemotaxis and swarming

, 2022
Neutrophils form part of the innate immune system, they are the most abundant circulating leukocytes in humans and play a crucial role in host defence and inflammation. Upon stimulation, neutrophils leave the blood stream and chemotax to sites of inflammation after which they employ a range of effectors functions to eliminate the threat.
openaire   +2 more sources

In the Eye of the Swarm: Unravelling Neutrophil Swarming Dynamics in Zebrafish [PDF]

Neutrophil dysfunctions are a major cause of chronic inflammatory diseases like COPD, but also infectious diseases such as COVID-19. Understanding neutrophil behaviour and pathways can lead to new therapeutic approaches aiding to relieve the burden of ...
Olijhoek, Nils Ingmar
core  

TSP1/TGF-β1 drives arachidonic acid metabolism to orchestrate neutrophil swarming

Summary Neutrophil swarming has emerged as a conserved multicellular behaviour observed across tissues and pathological contexts. Yet, the molecular cues and the spatially coordinated cellular circuits that drive the process of neutrophil swarming leading to cluster formation remain poorly understood. Here, we combine spatial proteomics
Lars Widera, Philippa Spangenberg, Devon Siemes, Sebastian Bessler, Jenny Bottek, Hannah Voss, Angelo Novak, Darleen Hueser, Mathis Richter, Alexander Potthoff, Bente Siebels, Manuela Moritz, Antonia Gocke, Stephanie Thiebes, Stephanie Tautges, Triantafyllos Chavakis, Jadwiga Jablonska, Tim Lämmermann, Matthias Gunzer, Hartmut Schlüter, Jan Hahn, Anika Grüneboom, Oliver Soehnlein, Klaus Dreisewerd, Jens Soltwisch, Olga Shevchuk, Daniel R. Engel   +26 more
openaire   +1 more source

Design and implementation of workflow tools for multiplexed time-lapse imaging experiments in zebrafish screening [PDF]

Recent high-throughput microscopy advancements have made it possible to perform multiplexed time-lapse imaging in a single experimental run. However, despite these technological improvements, a major gap remains in the practical application and ...
Satheesan, Sankeert
core   +1 more source