Results 41 to 50 of about 2,507 (174)

Convolution of chemoattractant secretion rate, source density, and receptor desensitization direct diverse migration patterns in leukocytes [PDF]

, 2012
Chemoattractants regulate diverse immunological, developmental, and pathological processes, but how cell migration patterns are shaped by attractant production in tissues remains incompletely understood.
Irvine, Darrell J, Wang, Yana
core   +1 more source

Chitotriosidase Activity Is Counterproductive in a Mouse Model of Systemic Candidiasis

Frontiers in Immunology, 2021
Mammalian cells do not produce chitin, an insoluble polymer of N-acetyl-D-glucosamine (GlcNAc), although chitin is a structural component of the cell wall of pathogenic microorganisms such as Candida albicans.
Nicholas A. Schmitz, Ritesh P. Thakare, Chun-Shiang Chung, Chang-Min Lee, Jack A. Elias, Chun Geun Lee, Brian W. LeBlanc   +6 more
doaj   +1 more source

Neutrophils are required for both the sensitization and elicitation phase of contact hypersensitivity [PDF]

, 2014
Allergic contact dermatitis and its animal model, contact hypersensitivity (CHS), are T cell-mediated inflammatory skin diseases induced by contact allergens.
Anne Dudeck, Attila Mócsai, Axel Roers, Béla Ozsvári, Charmoy, Chtanova, Clausen, Cumberbatch, Dudeck, Dunay, Dzhagalov, Engeman, Esser, Eva Oswald, Felix C. Weber, Futosi, Goebeler, Hermans, Jakus, Janka Z. Csepregi, Kim, Kovács, Lopez, László G. Puskás, Mantovani, Martin, Martin, Martin, Mócsai, Németh, Schmidt, Sesarman, Shornick, Stefan F. Martin, Tamás Németh, Thilo Jakob, Vocanson, Wang, Weber, Wojtasiak   +39 more
core   +1 more source

Neutrophils in cancer: neutral no more [PDF]

, 2016
Neutrophils are indispensable antagonists of microbial infection and facilitators of wound healing. In the cancer setting, a newfound appreciation for neutrophils has come into view.
A Blaisdell, A Carus, A Görgens, A Hasenberg, A Kohler, A Mantovani, A Sparmann, A Stoppacciaro, A Swierczak, A Warnatsch, AD Friedman, AD Panopoulos, AJ Casbon, AJ Gentles, AJ Templeton, AK Mankan, AM Houghton, AM Wengner, AP Tittel, AS Chung, B Ruffell, BK Popivanova, BT Suratt, BZ Qian, C Cheretakis, C Gordy, C Martin, CF Wu, CH Ries, CL Semerad, CL Semerad, D Di Mitri, D Marvel, D Metcalf, D Zhang, DI Gabrilovich, DJ Cua, DR Welch, E Elinav, EB Eruslanov, EI Deryugina, EM Bekes, F Chen, F Colotta, F Kuonen, F Liu, F Liu, F Rosenbauer, F Shojaei, F Shojaei, F Shojaei, F Shojaei, G Molineux, G Wang, GJ Guthrie, GJ Lieschke, GO Ahn, H Hirai, H Ji, H Katoh, H Nozawa, H Takahashi, H Tazawa, HH Yan, HK Jensen, HK Kim, HL Rao, HS Deshmukh, I Mishalian, I Petit, J Adolfsson, J Cools-Lartigue, J Crawford, J Jablonska, J Jiao, J Mei, J Pillay, J Pillay, J Pillay, J Sceneay, JC Pahler, JD Spicer, JD Waight, JD Waight, JF Seymour, JI Youn, JI Youn, JL Granick, JL Guerriero, JM Daley, JM Petty, JP Levesque, JT Dancey, JT Erler, JY Sagiv, K Fiedler, K Kersten, K Kim, K Shang, K Shitara, K Tomihara, KA Charles, Karin E. de Visser, KE De Visser, KH Steinbach, KJ Eash, KJ Eash, L Benevides, L Deng, L Gong, L Strauss, L Yang, L Yang, LA Pekarek, LB Rivera, LJ Bayne, LM Coussens, LP Seung, M Bodogai, M Bruchard, M Di Maio, M Elkabets, M Hager, M Ishikawa, M Kowanetz, M Papaspyridonos, M Santoni, M Van Egmond, M Wislez, MA Lopez-Lago, MA Postow, MA Stark, Max D. Wellenstein, MF Denny, MG Manz, MH Kim, MK Richards, MK Srivastava, MP Keane, MT O'Toole, N Antonio, N Borregaard, N Borregaard, P Andreu, P Ehrlich, P Schwarzenberger, P Wu, PC Burdon, PC Vincent, PJ Murray, Q Ma, R Bertini, R Catena, R Noy, RA Caruso, RA Droeser, RN Kaplan, S Acharyya, S Basu, S Dogan, S Hiratsuka, S Tazzyman, S Tazzyman, S Tu, SB Coffelt, SB Coffelt, SB Forlow, Seth B. Coffelt, SH Chang, SH Saverymuttu, SI Rennard, SJ Huh, SJ Moghaddam, SK Bunt, SK Wculek, SL Gaffen, SL Highfill, T Bald, T El Rayes, T Jamieson, T Kitamura, T Lämmermann, T Tak, T Voloshin, T Yamanaka, TE Sutherland, TO Jensen, V Cortez-Retamozo, V Finisguerra, VT Phan, WJ McKinstry, X Qu, X Song, XD Yang, Y Carmi, Y Han, Y Ma, Y Pang, Y Pylayeva-Gupta, Y Sawanobori, Y Tsuda, Y Ueda, Y Ueda, Z Granot, Z Li, ZG Fridlender   +205 more
core   +1 more source

Pseudomonas aeruginosa mexR and mexEF Antibiotic Efflux Pump Variants Exhibit Increased Virulence

Antibiotics, 2021
Antibiotic-resistant Pseudomonas aeruginosa infections are the primary cause of mortality in people with cystic fibrosis (CF). Yet, it has only recently become appreciated that resistance mutations can also increase P.
Mylene Vaillancourt, Sam P. Limsuwannarot, Catherine Bresee, Rahgavi Poopalarajah, Peter Jorth   +4 more
doaj   +1 more source

Genomic analysis and immune response in a murine mastitis model of vB_EcoM-UFV13, a potential biocontrol agent for use in dairy cows [PDF]

, 2018
Bovine mastitis remains the main cause of economic losses for dairy farmers. Mammary pathogenic Escherichia coli (MPEC) is related to an acute mastitis and its treatment is still based on the use of antibiotics.
Campanaro, Stefano, Crispim, Josicelli Souza, da Silva, Cynthia Canedo, de Paula, Sergio Oliveira, Dias, Roberto Sousa, Duarte, Vinicius da Silva, Ferro, Camila Geovana, Kropinski, Andrew M., Martins, Franciele, Paes, Isabela da Silva, Santana, Gabriele Rocha, Siqueira, Carolina, Treu, Laura, Vidigal, Pedro M. P., Vieira, Marcella Silva, Xavier, Andre da Silva   +15 more
core   +2 more sources

Recent Advances in Collective Behaviors of Micro/Nanomotor Swarms. [PDF]

Adv Mater
This review describes the driving forces behind collective motion, explores the self‐organization of micro/nano swarms across zero‐dimensional (0D), one‐dimensional (1D), two‐dimensional (2D), and three‐dimensional (3D) spaces, and highlights their potential in drug delivery, environmental monitoring, and smart devices.
Sun S, Sun B, Cook AB, Padial TP, van Hest JCM.   +4 more
europepmc   +2 more sources

A novel cellular pathway of antigen presentation and CD4 T cell activation in vivo [PDF]

, 2018
Dendritic cell activation of CD4 T cells in the lymph node draining a site of infection or vaccination is widely considered the central event in initiating adaptive immunity.
Baz Morelli, Adriana, Benson, Robert A., Brewer, James M., Garside, Paul, Hayes, Alan J., Maraskovsky, Eugene, Meehan, Gavin R., Scales, Hannah E., Tomura, Michio, Walters, Anne, Watson, Emma   +10 more
core   +3 more sources

Self-extinguishing relay waves enable homeostatic control of human neutrophil swarming

, 2023
Neutrophils exhibit self-amplified swarming to sites of injury and infection. How swarming is controlled to ensure the proper level of neutrophil recruitment is unknown. Using an ex vivo model of infection, we find that human neutrophils use active relay to generate multiple pulsatile waves of ...
Evelyn Strickland, Deng Pan, Christian Godfrey, Julia S. Kim, Alex Hopke, Maureen Degrange, Bryant Villavicencio, Michael K. Mansour, Christa S. Zerbe, Daniel Irimia, Ariel Amir, Orion D. Weiner   +11 more
openaire   +2 more sources

Marginal Zone B Cells Assist With Neutrophil Accumulation to Fight Against Systemic Staphylococcus aureus Infection

Frontiers in Immunology, 2021
In addition to regulating immune responses by producing antibodies that confer humoral immunity, B cells can also affect these responses by producing cytokines.
Li-Wen Lo, Li-Wen Lo, Chia-Wei Chang, Ming-Feng Chiang, I-Ying Lin, Kuo-I Lin, Kuo-I Lin   +6 more
doaj   +1 more source