Results 61 to 70 of about 2,507 (174)

Phenotypic Evolution of Therapeutic Salmonella enterica Serovar Typhimurium after Invasion of TRAMP Mouse Prostate Tumor [PDF]

, 2014
Salmonella has been of interest in cancer research due to its intrinsic ability to selectively target and colonize within tumors, leading to tumor cell death.
Choe, Elizabeth, Eisenstark, Abraham, Kazmierczak, Robert A.   +2 more
core   +2 more sources

Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis [PDF]

, 2015
Pseudomonas aeruginosa produces quorum sensing signal molecules that are potential biomarkers for infection. A prospective study of 60 cystic fibrosis patients with chronic P. aeruginosa, who required intravenous antibiotics for pulmonary exacerbations,
Alan J. Knox, Alan R. Smyth, Andrew Clayton, Andrew W. Fogarty, David A. Barrett, David Honeybourne, Douglas L. Forrester, Edward F. Nash, Helen L. Barr, Jaffar-Bandjee, Jane Dewar, Joanna L. Whitehouse, Miguel Cámara, Nigel Halliday, Paul Williams, Rebecca Simms   +15 more
core   +2 more sources

The cytochrome bd-I respiratory oxidase augments survival of multidrug-resistant Escherichia coli during infection [PDF]

, 2016
Nitric oxide (NO) is a toxic free radical produced by neutrophils and macrophages in response to infection. Uropathogenic Escherichia coli (UPEC) induces a variety of defence mechanisms in response to NO, including direct NO detoxification (Hmp, NorVW ...
A Hausladen, AJ Carey, AJ Carey, BM Forde, CE Vine, CS Bang, DT Hess, E Hernandez-Urzua, EC Hagan, FR Blattner, H Cruz-Ramos, HL Mobley, HN Wang, IU Mysorekar, J Flatley, J Membrillo-Hernandez, J Stachura, JA Kers, JB Vicente, JH van Wonderen, JON Lundberg, K Schroder, KA Datsenko, KWW Chen, L Svensson, LP Allsopp, LV Holyoake, M Poljakovic, M Totsika, MA Ingersoll, MA Wheeler, MD Phan, MES Achard, MG Mason, N Barraud, NK Petty, NL Ben Zakour, P Andersson, PA Cotter, PA Cotter, PC Mills, RA Hull, S Adak, S Mohr, S Sarkar, SE Chesrown, SE Chesrown, SO Kim, ST Pullan, TM Stevanin, TW Hart, WE Stamm, WS Choi, Z Wang   +53 more
core   +3 more sources

Information Transmission Strategies for Self‐Organized Robotic Aggregation

Advanced Robotics Research, EarlyView.
In this review, we discuss how information transmission influences the neighbor‐based self‐organized aggregation of swarm robots. We focus specifically on local interactions regarding information transfer and categorize previous studies based on the functions of the information exchanged.
Shu Leng, Zihan Li, Yifeng Shao, Jinhao Liu, Li Yu, Shuguang Li   +5 more
wiley   +1 more source

In the eye of the neutrophil swarm—navigation signals that bring neutrophils together in inflamed and infected tissues [PDF]

Journal of Leukocyte Biology, 2015
Abstract Neutrophils are sentinel cells that express in higher vertebrates >30 chemokine and chemoattractant receptors to sense and quickly react to tissue damage signals. Intravital microscopy studies in mouse models of wounding, inflammation, and infection have revealed that neutrophils form cell swarms at local sites of tissue ...
openaire   +3 more sources

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to Candida Species

mBio, 2020
Invasive fungal infections constitute a lethal threat, with patient mortality as high as 90%. The incidence of invasive fungal infections is increasing, especially in the setting of patients receiving immunomodulatory agents, chemotherapy, or ...
Paige E. Negoro, Shuying Xu, Zeina Dagher, Alex Hopke, Jennifer L. Reedy, Michael B. Feldman, Nida S. Khan, Adam L. Viens, Natalie J. Alexander, Natalie J. Atallah, Allison K. Scherer, Richard A. Dutko, Jane Jeffery, John F. Kernien, J. Scott Fites, Jeniel E. Nett, Bruce S. Klein, Jatin M. Vyas, Daniel Irimia, David B. Sykes, Michael K. Mansour   +20 more
doaj   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Bacterial infections in cirrhosis: Role of proton pump inhibitors and intestinal permeability [PDF]

, 2012
Background Cirrhotic patients are at considerable risk for bacterial infections, possibly through increased intestinal permeability and bacterial overgrowth. Proton pump inhibitors (PPIs) may increase infection risk.
Erpecum, K.J. (Karel) van, Hoek, B. (Bart) van, Huisman, E.J. (Ellen), Renooij, W. (W.), Rooij, F.W.M. (Felix) de, Siersema, P.D. (Peter), Vlerken, L.G. (Lotte) van   +6 more
core   +1 more source

Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis

Advanced Science, EarlyView.
HSP90α is significantly upregulated in platelets from sepsis patients, with its origin from megakaryocyte‐derived trafficking. Furthermore, activated platelets secrete HSP90α into the extracellular space in both free and exosome‐associated forms. Finally, extracellular HSP90α directly engages TLR4 on neutrophils to induce autophagy, leading to NET ...
Chengbo Wang, Maodong Leng, Chenchen Sun, Jingyu Cao, Linfei Li, Yangyang Jia, Yongshuai Han, Yuchun Liu, Yaodong Zhang, Chenglong Zhang, Yingli Men, Ningyuan Liu, Yibing Cheng, Yixia Zhang, Ya Li, Zhenlong Li, Lidan Cui, Xiangzhan Zhu   +17 more
wiley   +1 more source