Results 51 to 60 of about 13,856 (332)

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Predictive value of hematological and phenotypical parameters on postchemotherapy leukocyte recovery [PDF]

, 2009
Background: Grade IV chemotherapy toxicity is defined as absolute neutrophil count <500/μL. The nadir is considered as the lowest neutrophil number following chemotherapy, and generally is not expected before the 7th day from the start of chemotherapy.
Abbasciano V, Albertini F, Barile C, Bononi A, CAMPIONI, Diana, Crepaldi G, Ferrari L, Ferrazzi E, Gilli G, Gusella M, Lanza F, Menon D, Pasini F., Russo A, Stievano L, Toso S   +15 more
core   +1 more source

Recent advances in mRNA-LNP therapeutics: immunological and pharmacological aspects

Journal of Nanobiotechnology, 2022
In the last decade, the development of messenger RNA (mRNA) therapeutics by lipid nanoparticles (LNP) leads to facilitate clinical trial recruitment, which improves the efficacy of treatment modality to a large extent. Although mRNA-LNP vaccine platforms
Seyed Hossein Kiaie, Naime Majidi Zolbanin, Armin Ahmadi, Rafieh Bagherifar, Hadi Valizadeh, Fatah Kashanchi, Reza Jafari   +6 more
doaj   +1 more source

The Neutrophil [PDF]

, 2007
The neutrophil provides a crucial defence against fungal infections. This numerous phagocyte is recruited rapidly to sites of infection, where it detects pathogens through a range of pathogen-recognition receptors. Phagocytosis and the generation of a range of microbicidal molecules neutralises the pathogen, following which neutrophil death by ...
Dockrell, David H., McGrath, Emmet E., Whyte, Moria K.B., Sabroe, Ian   +3 more
openaire   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

CONTENTS OF LYMPHOCYTE SUB-POPULATIONS IN THE CHILDREN WITH ACUTE LEUKEMIA AND LYMPHOMAS DEPENDENT ON INFECTIOUS COMPLICATION AND NEUTROPENIA

Медицинская иммунология, 2014
. The aim of the present work was to evaluate the contents of some lymphocyte sub-populations in peripheral blood of the children with tumors of hematopoietic and lymphoid tissues, depending on infectious complication of cytostatic therapy and ...
M. V. Peshikova, I. I. Dolgushin, O. L. Kolesnikov, N. N. Rusanova   +3 more
doaj   +3 more sources

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Effet modulatoire des nanoparticules de TIO₂, CEO₂ et ZNO sur la dégranulation chez le neutrophile humain [PDF]

, 2014
Les nanoparticules (NPs) de dioxyde de cérium (Ce02), dioxyde de zinc (ZnO) et dioxyde de titane (Ti02) sont des oxydes métalliques retrouvés grandement dans l'environnement, au sein des domaines tels que les industries pharmaceutiques, électroniques ...
Babin, Kim
core  

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Der Einfluss der neutrophilen Granulozyten und des zirkadianen Rhythmus auf die Wundheilung nach einem Myokardinfarkt [PDF]

, 2018
Kardiovaskuläre Erkrankungen und insbesondere der akute Myokardinfarkt sind die häufigste Todesursache in der entwickelten Welt. Das Überleben von Patienten mit einem akuten Myokardinfarkt wird wesentlich durch eine adäquat balancierte ...
Schloss, Maximilian J.
core