Results 71 to 80 of about 13,856 (332)

Application of dicarbamin in treatment of patients by a chronic hepatitis C

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2011
Aim of investigation. Studying of clinical and laboratory efficacy of dicarbamin as hematoprotector in patients with chronic hepatitis C (CHC) with 1b virus genotype at combined antiviral therapy (AVT) by pegilated interferons in combination to ribavirin.
D. Yu. Konstantinov, Ye. A. Konstantinova, L. L. Popova, E. A. Strebkova, A. A. Suzdaltsev   +4 more
doaj  

Neutrophil extracellular traps — the dark side of neutrophils [PDF]

Journal of Clinical Investigation, 2016
Neutrophil extracellular traps (NETs) were discovered as extracellular strands of decondensed DNA in complex with histones and granule proteins, which were expelled from dying neutrophils to ensnare and kill microbes. NETs are formed during infection in vivo by mechanisms different from those originally described in vitro. Citrullination of histones by
Sørensen, Ole E., Borregaard, Niels
openaire   +4 more sources

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source

Production et évaluation de l'anticorps NIMP-R14 pour dépléter chroniquement les neutrophiles chez un modèle expérimental d'athérosclérose avancée : la souris ApoE-/- 2 reins-1clip (2K1C) [PDF]

, 2012
L'athérosclérose (ATS) est une maladie artérielle inflammatoire chronique à l'origine des nombreuses maladies cardiovasculaires que sont l'infarctus du myocarde, l'accident vasculaire cérébral ou encore l'artériopathie oblitérante des membres inférieurs.
Azizi, A.
core  

Baseline MELD score predicts hepatic decompensation during antiviral therapy in patients with chronic hepatitis C and advanced cirrhosis [PDF]

, 2013
Background and Aims: In patients with advanced liver cirrhosis due to chronic hepatitis C virus (HCV) infection antiviral therapy with peginterferon and ribavirin is feasible in selected cases only due to potentially life-threatening side effects ...
Dultz, Georg, Friedrich-Rust, Mireen, Herrmann, Eva, Hofmann, Wolf Peter, Kronenberger, Bernd, Sarrazin, Christoph, Seelhof, Martin, Teuber, Gerlinde, Vermehren, Johannes, Wagner, Michael von, Welker, Martin-Walter, Zeuzem, Stefan   +11 more
core   +2 more sources

Inflammatory marker comparison in childhood brucellosis: predicting osteoarticular involvement

The Turkish Journal of Pediatrics
Background. Although the use of inflammatory markers in diagnosing Brucella-related complications has been the subject of research, studies on osteoarticular disease are insufficient, especially in children.
Elif Böncüoğlu, Şadiye Kübra Tüter Öz, Zafer Bağcı   +2 more
doaj   +1 more source

Utilizing peripheral blood inflammatory biomarker (PBIB) to predict response to systemic therapy in patients with breast cancer

Journal of Family Medicine and Primary Care, 2023
Background: Inflammation is a recognized factor in cancer progression and resistance to treatments. Several studies correlated inflammation-related peripheral blood inflammatory biomarkers (PBIB) to disease progression and poor survival in various cancer
Atlal Abusanad
doaj   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Neutrophil and neutrophil extracellular trap involvement in neutrophilic asthma: A review

Medicine
Asthma is a highly prevalent chronic inflammatory disease characterized by variable airflow obstruction and airway hyperresponsiveness. Neutrophilic asthma (NA) is classified as “type 2 low” asthma, defined as 65% or more neutrophils in the total cell count.
Yuemu Li, Tianyi Yang, Baihua Jiang
openaire   +2 more sources

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source