Results 41 to 50 of about 94,980 (286)

Neutrophilic Asthma Is Associated With Smoking, High Numbers of IRF5+, and Low Numbers of IL10+ Macrophages

Frontiers in Allergy, 2021
Asthma is a heterogenous disease with different inflammatory subgroups that differ in disease severity. This disease variation is hampering treatment and development of new treatment strategies.
Nil Turan, T. Anienke van der Veen, T. Anienke van der Veen, Christina Draijer, Christina Draijer, Fatemeh Fattahi, Fatemeh Fattahi, Fatemeh Fattahi, Nick H. ten Hacken, Nick H. ten Hacken, Wim Timens, Wim Timens, Antoon J. van Oosterhout, Maarten van den Berge, Maarten van den Berge, Barbro N. Melgert, Barbro N. Melgert, Barbro N. Melgert   +17 more
doaj   +1 more source

Is pesticide exposure a cause of obstructive airways disease? [PDF]

, 2014
Peer reviewedPublisher ...
Ayres, Jon G., Cowie, Hilary, Crawford, Joanne O, Devereux, Graham, Dick, Finlay, Dixon, Ken, Doust, Emma   +6 more
core   +2 more sources

A tetraspecific VHH-based neutralizing antibody modifies disease outcome in three animal models of Clostridium difficile infection [PDF]

, 2016
Clostridium difficile infection (CDI), a leading cause of nosocomial infection, is a serious disease in North America, Europe, and Asia. CDI varies greatly from asymptomatic carriage to life-threatening diarrhea, toxic megacolon, and toxemia.
Beamer, Gillian, Curiel, David T, Debatis, Michele, Dmitriev, Igor P, Kashentseva, Elena A, Kim, Hyeun Bum, Schmidt, Diane J, Shoemaker, Charles B, Steele, Jennifer A, Sun, Xingmin, Tremblay, Jacqueline M, Tzipori, Saul, Wang, Yaunkai   +12 more
core   +2 more sources

Palisaded neutrophilic and granulomatous dermatitis following a long-standing monoclonal gammopathy: A case report

SAGE Open Medical Case Reports, 2021
Background: Palisaded neutrophilic granulomatous dermatitis is a rare inflammatory dermatosis with possible underlying systemic conditions including rheumatoid arthritis, autoimmune connective tissue disease, and malignancies.
Dorsa Zabihi-pour, Bahar Bahrani, Dalal Assaad, Jensen Yeung   +3 more
doaj   +1 more source

Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. [PDF]

, 2014
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus ...
Butcher, Brad, Carlson, Adam Q, Graf, Jonathan, Imboden, John B, Jen, Kuang-Yu, Sam, Ramin, Tuot, Delphine S   +6 more
core   +2 more sources

Nb2C‐Reinforced Hydrogel Microneedle as Dual ROS‐Scavenging Platform to Promote Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
An advanced microneedle patch integrating niobium carbide nanosheets and curcumin is engineered for diabetic wound healing. The system enables dual ROS scavenging and NIR‐enhanced antimicrobial activity, effectively rebalancing the oxidative microenvironment, promoting macrophage repolarization and angiogenesis, and accelerating full‐thickness wound ...
Zhi Zheng, Heyan Huang, Xiangru Chen, Jie Fu, Zhiwei Sun, Mengjuan Tao, Jianwei Mao, Fei Zhang, Zhou Wan, Yuan Li, Dingan Wu, Chuchao Zhou, Yanqing Yang   +12 more
wiley   +1 more source

Oral supplementation of medium-chain fatty acids during the dry period supports the neutrophil viability of peripartum dairy cows [PDF]

, 2013
A randomised clinical trial was conducted to explore the effect of orally supplemented medium-chain fatty acids (MCFA) to heifers and cows starting 6-8 weeks prior to expected calving date on blood and milk polymorphonuclear neutrophilic leucocyte (PMNL)
De Vliegher, Sarne, Piepers, Sofie
core   +2 more sources

Bifidobacterium Breve Yang08 Alleviates Atopic Dermatitis By Enriching Akkermansia Muciniphila and Inhibiting Neutrophil Extracellular Traps Formation In Mice

Advanced Science, EarlyView.
A novel Bifidobacterium breve strain, Yang08, is isolated to counter its depletion in atopic dermatitis. In mice, live Yang08 requires an intact gut microbiota to exert protection, specifically enriching Akkermansia muciniphila and potently inhibiting pathogenic neutrophil activation and NETosis in the skin.
Yanqiang Shi, Shuang He, Chengyi Li, Hung Chan, Zhenfeng Liu, Bin Yang, Qing Li   +6 more
wiley   +1 more source

The clinical significance of neutrophilic pleocytosis in cerebrospinal fluid in patients with viral central nervous system infections

International Journal of Infectious Diseases, 2017
Background: Viral central nervous system (CNS) infections are typically characterized by a cerebrospinal fluid (CSF) lymphocytic pleocytosis. A CSF neutrophilic pleocytosis presentation has been described, but its prognostic and clinical significance is ...
Siraya Jaijakul, Lucrecia Salazar, Susan H. Wootton, Elizabeth Aguilera, Rodrigo Hasbun   +4 more
doaj   +1 more source

Macrophage and dendritic cell subset composition can distinguish endotypes in adjuvant-induced asthma mouse models.

PLoS ONE, 2021
Asthma is a heterogeneous disease with neutrophilic and eosinophilic asthma as the main endotypes that are distinguished according to the cells recruited to the airways and the related pathology.
Müge Özkan, Yusuf Cem Eskiocak, Gerhard Wingender   +2 more
doaj   +1 more source