Anti-inflammatory effect of Trichospira verticillata via suppression of the NLRP3 inflammasome in neutrophilic asthma. [PDF]
Yang H +10 more
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Aspergillus fumigatus binding IgA and IgG1 are increased in bronchoalveolar lavage fluid of horses with neutrophilic asthma. [PDF]
Jentsch MC +8 more
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MicroRNAs as Biomarkers in Corticosteroid-Resistant/Neutrophilic Asthma: Still a Long Way to Go! [PDF]
Ricciardolo FLM, Carriero V, Bullone M.
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Correction for: Neutrophil extracellular traps amplify neutrophil recruitment and inflammation in neutrophilic asthma by stimulating the airway epithelial cells to activate the TLR4/ NF-κB pathway and secrete chemokines. [PDF]
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Neutrophil chemotactic factors in asthma.
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Asthma is a complex disease with a significant inflammatory component. Multiple cell types are involved in its pathophysiology. The presence of eosinophils, the cell usually associated with allergic diseases, does not fully explain the inflammation found in asthma.
Ana L, Macdowell, Stephen P, Peters
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Refractory neutrophilic asthma and ciliary genes
Journal of Allergy and Clinical Immunology, 2022Refractory asthma (RA) remains poorly controlled, resulting in high health care utilization despite guideline-based therapies. Patients with RA manifest higher neutrophilia as a result of increased airway inflammation and subclinical infection, the underlying mechanisms of which remain unclear.We sought to characterize and clinically correlate gene ...
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Neutrophils in asthma—A review
Respiratory Physiology & Neurobiology, 2015Asthma is a chronic inflammatory disease, with an array of cells involved in the pathogenesis of the disease. The role of neutrophils in the development of bronchial asthma is found to be complex, as they may trigger activation of immunocompetent cells and are a potent source of free oxygen radicals and enzymes participating in airway remodeling.
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Neutrophil activation in occupational asthma
Current Opinion in Allergy & Clinical Immunology, 2019Purpose of review The aim of this review is to emphasize the role of neutrophils in patients with occupational asthma. This review facilitates a better understanding, accurate diagnosis, and proper management of asthmatic reactions provoked at the workplace.
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Eosinophilic vs. Neutrophilic Asthma
Current Pulmonology Reports, 2020Understanding the molecular mechanisms and heterogeneity of asthma has allowed the discovery of two distinct endotypes based on the mechanisms driving the underlying airway inflammation: eosinophilic asthma, a subtype of T2-high asthma, and neutrophilic asthma, a subtype of non-T2 asthma or T2-low asthma.
Sara M. Assaf, Nicola A. Hanania
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