Results 181 to 190 of about 24,238 (217)

Persistent neutrophil activation in mild asthma

Journal of Allergy and Clinical Immunology, 1992
allergic cutaneous inflammation in viva. J Immunol 1991;146:521-8. 4. Bochner BS, Peachell PT, Brown KE, Schleimer RP. Adherence of human basophils to cultured umbilical vein vascular endothelial cells. J Clin Invest 1988;81:1355-60. 5. Kyan-Aung U, Haskard DO, Lee TH. Vascular cell adhesion molecule-l (VCAM-1) and eosinophil adhesion to cultured human
J, Kallenbach, R, Baynes, B, Fine, D, Dajee, W, Bezwoda   +4 more
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Neutrophilic Asthma and Potentially Related Target Therapies

Current Drug Targets, 2020
Background: Neutrophilic asthma is generally associated with the absence of eosinophils and activation of non- predominant type 2 immunological pathways. It involves bronchial inflammation followed by different degrees of airway remodeling. Neutrophilic inflammation activates specific cellular and molecular pathways due to inhalation of environmental ...
Pranav Nair, Kedar S. Prabhavalkar
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The Role of Neutrophils in Asthma

Immunology and Allergy Clinics of North America, 2018
Although asthma defines a syndrome associated with airway inflammation, heterogeneity exists concerning the type of inflammation that modulates airway hyperresponsiveness. Compelling evidence suggests that common triggers of asthma exacerbations are preferentially mediated by neutrophilic airway inflammation.
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Neutrophil chemotactic activity in milk-induced asthma

Journal of Allergy and Clinical Immunology, 1983
Four subjects with clinical histories of milk-induced asthma were studied (three allergic to cow's milk; one to soya milk). In each instance, skin prick tests, RAST (IgE and IgG4), the basophil histamine release, and serum precipitins, using appropriate milk extracts, were negative.
N, Papageorgiou, T H, Lee, T, Nagakura, O, Cromwell, D G, Wraith, A B, Kay   +5 more
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Evidence for neutrophil activation in occupational asthma

Respirology, 1999
AbstractIn order to evaluate the role of neutrophils in the pathogenesis of occupational asthma (OA), 15 toluene diisocyanate (TDI)‐asthma and six grain dust‐asthma patients were recruited. Controls were the same number of subjects showing negative bronchoprovocation test (BPT) and six house dust mite‐sensitive asthma.
K S, Jung, H S, Park
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Formoterol Attenuates Neutrophilic Airway Inflammation in Asthma

Chest, 2005
Airway neutrophil levels are increased in patients with severe asthma and during asthma exacerbations. Long-acting beta2-agonists (LABAs), such as formoterol, reduce the number of asthma exacerbations. While beta2-agonists may affect neutrophil function in vitro, it is uncertain whether they have effects on neutrophilic inflammation in asthmatic ...
Kittipong, Maneechotesuwan, Sarah, Essilfie-Quaye, Sally, Meah, Claire, Kelly, Sergei A, Kharitonov, Ian M, Adcock, Peter J, Barnes   +6 more
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Neutrophils and asthma.

1998
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FABBRI, Leonardo, BOSCHETTO, Piera, CARAMORI, Gaetano, MAESTRELLI, Piero   +3 more
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Asthma Management by Monitoring Sputum Neutrophil Count

Chest, 2008
We report the utility of quantitative cell counts in sputum in monitoring therapy of a patient with poorly controlled asthma. Recurrent neutrophilic bronchitis without an eosinophilic bronchitis led to the identification of Chlamydophila pneumoniae as the cause of bronchitis and asthma exacerbation.
Shelley, Pallan, James B, Mahony, Paul M, O'Byrne, Parameswaran, Nair   +3 more
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Bronchial asthma and the neutrophil chemotactic factor

Clinical & Experimental Allergy, 1982
Neutrophil chemotactic factor (NCF) is a slight acidic macromolecule which is released into the circulation of asthmatic individuals following antigen provocation and an exercise task. It also appears in late asthmatic reactions with a time course of appearance which precedes the second fall in FEV1.
T H, Lee, A B, Kay
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Asthma. Eosinophils and neutrophils.

British medical bulletin, 1992
Eosinophils are strongly implicated as a major proinflammatory cell in the pathogenesis of asthma. Basic proteins from the crystalloid granule may be responsible for damage to mucosal epithelium whereas membrane-derived lipid mediators (particularly platelet activating factor and leukotriene C4) might directly influence bronchial smooth muscle ...
A B, Kay, C J, Corrigan
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