Results 271 to 280 of about 1,037,717 (382)

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

Advanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu, Guoqing Jing, Shujuan Wu, Min Yuan, Yingyue Dong, Xue Chen, Huimin Zhou, Hailong Gong, Jing Zuo, Xiaojing Wu, Xuemin Song   +10 more
wiley   +1 more source

Obesity-Associated Metabolomic and Functional Reprogramming in Neutrophils from Horses with Asthma. [PDF]

Animals (Basel)
Albornoz A, Morales B, Fernandez VB, Henriquez C, Quiroga J, Alarcón P, Moran G, Burgos RA.   +7 more
europepmc   +1 more source

Antimicrobial proteins in bovine neutrophils [PDF]

, 1971
J. Brownlie
openalex   +1 more source

Targeting Cystine Metabolism in the Lung Cancer Environment Enhances the Efficacy of Immune Checkpoint Inhibition

Advanced Science, EarlyView.
The tumor‐associated macrophages (TAMs) in lung cancer tissues exhibit active cystine metabolism. Restricting cystine concentration in macrophages induces M1 phenotypic polarization and upregulation of PD‐L1 expression through the GSH‐NF‐κB signaling pathway.
Yun Xu, Shumin Li, Jiaji Wu, Shumin Xu, Mo Shen, Chenyang Wang, Lundqvist Andreas, Jianghao Yu, Zhiyong Xu, Yueli Shi, Nana Liu, Yunke Yang, Jiangnan Zhao, Ying Yang, Pingli Wang, Peng Yi, Jin Cheng, Junhui Sun, Mengshu Li, Peng Xiao, Kai Wang   +20 more
wiley   +1 more source

Immune Dysregulation and Prognosis in Sepsis: Insights From a Posttranslational Perspective. [PDF]

Hum Mutat
Ye Y, Chen Q, Wu D, Yu G, Liu J, Li Y, Xu Z, Lin L.   +7 more
europepmc   +1 more source

Interaction between the respiratory burst activity of neutrophil leukocytes and experimentally induced escherichia-coli mastitis in cows [PDF]

, 1990
Burvenich, Christian, Heyneman, Roger, Vercauteren, R   +2 more
core   +2 more sources

LASMA AND CELL‐DERIVED INHIBITORS OF HUMAN NEUTROPHIL CHEMOTAXIS [PDF]

, 1975
Edward J. Goetzl
openalex   +1 more source

Real‐Time Evolutionary Landscape of the Bronchial Epithelium and Corresponding Dynamic Immune Cell Alterations in Lung Squamous Cell Carcinogenesis

Advanced Science, EarlyView.
Lung squamous cell carcinoma (LUSC) is often preceded by sequential premalignant lesions with an increasing probability of malignant progression. Using single‐cell RNA sequencing, the dynamic cellular evolution from normal lung to LUSC tissues is delineated; clonal structure of premalignant and malignant epithelium is reveled; the conversion of immune ...
Baohong Luo, Yuting Luo, Sicheng Chen, Tiantian Yang, Bixia Liu, Xiting Liao, Xiaoke Zheng, Tian Tian, Jinxu Liu, Qinru Zhan, Xiaohua Situ, Zhongpeng Xie, Yanxia Wang, Zhe‐Sheng Chen, Honglei Chen, Zheng Yang, Zunfu Ke   +16 more
wiley   +1 more source

CD18 and CD36 expression in neutrophils from tumors and tumor-draining lymph nodes: implications for metastasis in oral squamous cell carcinoma. [PDF]

Clin Exp Metastasis
Ekstedt S, Cardenas EI, Piersiala K, Liljeström V, Petro M, Ezerskyte M, Farrajota Neves da Silva P, Kumlien Georén S, Cardell LO.   +8 more
europepmc   +1 more source

The particulate superoxide-forming system from human neutrophils. Properties of the system and further evidence supporting its participation in the respiratory burst. [PDF]

, 1976
Bernard Babior, J T Curnutte, B. Jane McMurrich   +2 more
openalex   +1 more source