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Neutrophil extracellular traps and neutrophilic asthma
Respiratory MedicineThere are more than 260 million asthma patients worldwide. How to provide targeted long-term standardized treatment and management still confuses clinical workers and patients. Neutrophilic asthma is a special type of asthma which is difficult to diagnose clinically and often associated with severe asthma and glucocorticoid resistance.
Jiayi, Xiang, Muyan, Cui, Yuling, Zhang
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Southern Medical Journal, 1982
A patient had chronic neutrophilic leukemia. The characteristic clinical features of this disease include long-standing neutrophilia in the absence of an underlying disease, marked granulocytic hyperplasia in the bone marrow, increased leukocyte alkaline phosphatase activity, and absence of Philadelphia chromosome in the marrow cells.
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A patient had chronic neutrophilic leukemia. The characteristic clinical features of this disease include long-standing neutrophilia in the absence of an underlying disease, marked granulocytic hyperplasia in the bone marrow, increased leukocyte alkaline phosphatase activity, and absence of Philadelphia chromosome in the marrow cells.
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Microbes and Infection, 2003
Phagocytosis is central to the microbicidal function of neutrophils. Pathogens are initially engulfed into a plasma membrane-derived vacuole, the phagosome, which proceeds to acquire degradative properties by a complex process termed maturation. In this chapter, we discuss the current knowledge of the molecular mechanisms underlying phagosome formation
Warren L, Lee +2 more
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Phagocytosis is central to the microbicidal function of neutrophils. Pathogens are initially engulfed into a plasma membrane-derived vacuole, the phagosome, which proceeds to acquire degradative properties by a complex process termed maturation. In this chapter, we discuss the current knowledge of the molecular mechanisms underlying phagosome formation
Warren L, Lee +2 more
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Transfusion Medicine Reviews, 2002
Antibodies to neutrophil antigens can cause neonatal alloimmune neutropenia, autoimmune neutropenia, febrile transfusion reactions, and transfusion-related acute lung injury. Several neutrophil antigen systems have been described serologically, but only the human neutrophil antigen-1 (HNA-1) or NA and HNA-2 or NB systems have been well characterized ...
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Antibodies to neutrophil antigens can cause neonatal alloimmune neutropenia, autoimmune neutropenia, febrile transfusion reactions, and transfusion-related acute lung injury. Several neutrophil antigen systems have been described serologically, but only the human neutrophil antigen-1 (HNA-1) or NA and HNA-2 or NB systems have been well characterized ...
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Current Opinion in Hematology, 1996
Neutrophils are the most abundant leukocytes and serve as a first line of defense against infectious microorganisms. For this purpose, neutrophils contain granules filled with proteolytic and other cytotoxic enzymes. Neutrophils have the shortest lifespan of all leukocytes.
C H, Homburg, D, Roos
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Neutrophils are the most abundant leukocytes and serve as a first line of defense against infectious microorganisms. For this purpose, neutrophils contain granules filled with proteolytic and other cytotoxic enzymes. Neutrophils have the shortest lifespan of all leukocytes.
C H, Homburg, D, Roos
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Journal of Leukocyte Biology
Abstract Ferroptosis is a distinct form of regulated cell death characterized by iron-dependent lipid peroxidation. The ferroptosis mechanism involves complex interactions between fatty acid metabolism, iron metabolism, lipid peroxidation, and antioxidative defense mechanisms.
Yu-Bin Lee +6 more
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Abstract Ferroptosis is a distinct form of regulated cell death characterized by iron-dependent lipid peroxidation. The ferroptosis mechanism involves complex interactions between fatty acid metabolism, iron metabolism, lipid peroxidation, and antioxidative defense mechanisms.
Yu-Bin Lee +6 more
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1984
Neutrophils are short-lived, highly specialized phagocytes. Their main function is to defend the host organism against invading microbes. The properties required to perform this function are chemotactic responsiveness, mobility, and the ability to phagocytose. Microorganisms are sensed through the chemotactic signals they emit or induce; are approached
M, Baggiolini, B, Dewald
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Neutrophils are short-lived, highly specialized phagocytes. Their main function is to defend the host organism against invading microbes. The properties required to perform this function are chemotactic responsiveness, mobility, and the ability to phagocytose. Microorganisms are sensed through the chemotactic signals they emit or induce; are approached
M, Baggiolini, B, Dewald
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1989
The red bone marrow — the source of all blood cells — is a large, but dispersed organ, about the size of the liver. In steady state, about 7 * 1010 mature neutrophilic granulocytes (hereafter called PMN-“polymorphonuclears” — or just granulocytes) – are mobilized daily from red bone marrow to blood.
H B, Benestad, O D, Laerum
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The red bone marrow — the source of all blood cells — is a large, but dispersed organ, about the size of the liver. In steady state, about 7 * 1010 mature neutrophilic granulocytes (hereafter called PMN-“polymorphonuclears” — or just granulocytes) – are mobilized daily from red bone marrow to blood.
H B, Benestad, O D, Laerum
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Dermatologic Clinics
Neutrophilic panniculitides are a heterogeneous group of inflammatory disorders encompassing many different entities. This review article focuses on the epidemiology, pathogenesis, clinicopathological features, diagnosis, and treatment of selected diseases.
Ganesh B, Maniam +4 more
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Neutrophilic panniculitides are a heterogeneous group of inflammatory disorders encompassing many different entities. This review article focuses on the epidemiology, pathogenesis, clinicopathological features, diagnosis, and treatment of selected diseases.
Ganesh B, Maniam +4 more
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Dermatologic Clinics, 2002
The neutrophilic dermatoses are a group of related cutaneous disorders that frequently have systemic manifestations or associations. While there are distinct clinical differences in the classical lesions of these disorders, there are many patients who have overlapping features.
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The neutrophilic dermatoses are a group of related cutaneous disorders that frequently have systemic manifestations or associations. While there are distinct clinical differences in the classical lesions of these disorders, there are many patients who have overlapping features.
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