Results 351 to 360 of about 1,037,717 (382)
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Developmental & Comparative Immunology, 2021
Since inflammasomes were discovered in the early 21st century, knowledge about their biology has multiplied exponentially. These cytosolic multiprotein complexes alert the immune system about the presence of infection or tissue damage, and regulate the subsequent inflammatory responses.
Victoriano Mulero +2 more
openaire +3 more sources
Since inflammasomes were discovered in the early 21st century, knowledge about their biology has multiplied exponentially. These cytosolic multiprotein complexes alert the immune system about the presence of infection or tissue damage, and regulate the subsequent inflammatory responses.
Victoriano Mulero +2 more
openaire +3 more sources
Neutrophils at the crossroads of innate and adaptive immunity
Journal of Leukocyte Biology, 2020Neutrophils are the most abundant leukocytes in blood. From the circulation, they are quickly mobilized to sites of inflammation and/or infection. At the affected tissues, neutrophils display an impressive array of antimicrobial functions, including ...
C. Rosales
semanticscholar +1 more source
Neutrophil chemotactic activity of rabbit neutrophils
Archives of Oral Biology, 1974Abstract Neutrophils regularly migrate into crevices of both healthy and inflamed gingiva. In the presence of inflamed gingiva, dental plaque supplies substances with a chemotactic effect on neutrophils. but the substances responsible for the attraction of neutrophils to crevices of healthy gingiva have not been identified.
Gunilla Tynelius-Bratthall, J. Lindhe
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Neutrophil extracellular traps: neutrophil’s afterlife
Hirurg (Surgeon), 2021This paper is a literature review on the origin, structure and functioning of neutrophil extracellular traps (NETs) that are released from neutrophils through NETosis, the kind of cell death. NETs are comprised of DNA, histones and neutrophil granule enzymes.
Viacheslav Nikolaevich Kravchuk +7 more
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Microbes and Infection, 2003
Phagocytosis is central to the microbicidal function of neutrophils. Pathogens are initially engulfed into a plasma membrane-derived vacuole, the phagosome, which proceeds to acquire degradative properties by a complex process termed maturation. In this chapter, we discuss the current knowledge of the molecular mechanisms underlying phagosome formation
Rene E. Harrison +2 more
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Phagocytosis is central to the microbicidal function of neutrophils. Pathogens are initially engulfed into a plasma membrane-derived vacuole, the phagosome, which proceeds to acquire degradative properties by a complex process termed maturation. In this chapter, we discuss the current knowledge of the molecular mechanisms underlying phagosome formation
Rene E. Harrison +2 more
openaire +3 more sources
Current Opinion in Hematology, 1996
Neutrophils are the most abundant leukocytes and serve as a first line of defense against infectious microorganisms. For this purpose, neutrophils contain granules filled with proteolytic and other cytotoxic enzymes. Neutrophils have the shortest lifespan of all leukocytes.
Dirk Roos, Christa H. E. Homburg
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Neutrophils are the most abundant leukocytes and serve as a first line of defense against infectious microorganisms. For this purpose, neutrophils contain granules filled with proteolytic and other cytotoxic enzymes. Neutrophils have the shortest lifespan of all leukocytes.
Dirk Roos, Christa H. E. Homburg
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The Neutrophil and Preeclampsia
Seminars in Reproductive Medicine, 1998Endothelial injury is common to all pathological features of preeclampsia. Neutrophil activation has been implicated in the pathophysiology of preeclampsia and requires binding and transmigration of neutrophils through the endothelium. This occurs via an interaction of endothelial adhesion molecules and surface receptors on neutrophils. Upon activation,
P Clark, F Boswell, I A Greer
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Current Allergy and Asthma Reports, 2007
Asthma is a complex disease with a significant inflammatory component. Multiple cell types are involved in its pathophysiology. The presence of eosinophils, the cell usually associated with allergic diseases, does not fully explain the inflammation found in asthma.
Ana L. MacDowell, Stephen P. Peters
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Asthma is a complex disease with a significant inflammatory component. Multiple cell types are involved in its pathophysiology. The presence of eosinophils, the cell usually associated with allergic diseases, does not fully explain the inflammation found in asthma.
Ana L. MacDowell, Stephen P. Peters
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Neutrophils in cancer: heterogeneous and multifaceted
Nature reviews. Immunology, 2021C. Hedrick, I. Malanchi
semanticscholar +1 more source
1984
Neutrophils are short-lived, highly specialized phagocytes. Their main function is to defend the host organism against invading microbes. The properties required to perform this function are chemotactic responsiveness, mobility, and the ability to phagocytose. Microorganisms are sensed through the chemotactic signals they emit or induce; are approached
Beatrice Dewald, Marco Baggiolini
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Neutrophils are short-lived, highly specialized phagocytes. Their main function is to defend the host organism against invading microbes. The properties required to perform this function are chemotactic responsiveness, mobility, and the ability to phagocytose. Microorganisms are sensed through the chemotactic signals they emit or induce; are approached
Beatrice Dewald, Marco Baggiolini
openaire +3 more sources