Results 361 to 370 of about 1,037,717 (382)
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Acta Haematologica, 2003
Regulation of the neutrophil life span by apoptosis provides a fine balance between their function as effector cells of host defense and a safe turnover of these potentially harmful cells. Alterations of neutrophil apoptosis are associated with a number of diseases.
Taco W. Kuijpers +3 more
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Regulation of the neutrophil life span by apoptosis provides a fine balance between their function as effector cells of host defense and a safe turnover of these potentially harmful cells. Alterations of neutrophil apoptosis are associated with a number of diseases.
Taco W. Kuijpers +3 more
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1989
The red bone marrow — the source of all blood cells — is a large, but dispersed organ, about the size of the liver. In steady state, about 7 * 1010 mature neutrophilic granulocytes (hereafter called PMN-“polymorphonuclears” — or just granulocytes) – are mobilized daily from red bone marrow to blood.
O. D. Laerum, H. B. Benestad
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The red bone marrow — the source of all blood cells — is a large, but dispersed organ, about the size of the liver. In steady state, about 7 * 1010 mature neutrophilic granulocytes (hereafter called PMN-“polymorphonuclears” — or just granulocytes) – are mobilized daily from red bone marrow to blood.
O. D. Laerum, H. B. Benestad
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British Medical Bulletin, 1984
Eosinophils are strongly implicated as a major proinflammatory cell in the pathogenesis of asthma. Basic proteins from the crystalloid granule may be responsible for damage to mucosal epithelium whereas membrane-derived lipid mediators (particularly platelet activating factor and leukotriene C4) might directly influence bronchial smooth muscle ...
A. B. Kay, Christopher Corrigan
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Eosinophils are strongly implicated as a major proinflammatory cell in the pathogenesis of asthma. Basic proteins from the crystalloid granule may be responsible for damage to mucosal epithelium whereas membrane-derived lipid mediators (particularly platelet activating factor and leukotriene C4) might directly influence bronchial smooth muscle ...
A. B. Kay, Christopher Corrigan
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Neutrophils as potential therapeutic targets in hepatocellular carcinoma
Nature reviews: Gastroenterology & hepatology, 2022D. Geh +5 more
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Neutrophil extracellular traps and neutrophilic asthma
Respiratory MedicineThere are more than 260 million asthma patients worldwide. How to provide targeted long-term standardized treatment and management still confuses clinical workers and patients. Neutrophilic asthma is a special type of asthma which is difficult to diagnose clinically and often associated with severe asthma and glucocorticoid resistance.
Jiayi Xiang, Muyan Cui, Yuling Zhang
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Elevated neutrophil function in chronic neutrophilic leukemia
American Journal of Hematology, 1992AbstractA 65‐year‐old man with marked leukocytosis was admitted for diagnosis and treatment. His peripheral blood leukocyte count was 37,500/μI and the leukocytes consisted of mature neutrophil‐like cells. A high neutrophil alkaline phosphatase score and a normal bone marrow cell karyotype suggested that the patient had chronic neutrophilic leukemia ...
Yoshifusa Matsuura +7 more
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The European respiratory journal. Supplement, 1989
The importance of inflammation in asthma has been recognized for a long time and recently proved in man and animal models. All inflammatory cells are probably involved in exacerbations of asthma. Neutrophils in particular are present in the airways during and after the spontaneous asthma attacks in man and during asthmatic reactions and airway ...
BOSCHETTO, Piera +3 more
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The importance of inflammation in asthma has been recognized for a long time and recently proved in man and animal models. All inflammatory cells are probably involved in exacerbations of asthma. Neutrophils in particular are present in the airways during and after the spontaneous asthma attacks in man and during asthmatic reactions and airway ...
BOSCHETTO, Piera +3 more
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Incidence of Neutrophil Antigens on Human Cord Neutrophils
American Journal of Reproductive Immunology, 1984ABSTRACT: Neutrophils isolated from cord blood of healthy newborns (33 blacks and 21 whites) were investigated by EDTA‐microagglutination for their expression of neutrophil specific antigens that have been associated with isoimmune neonatal or autoimmune neutropenia.
Prema R. Madyastha +2 more
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The Neutrophil Nucleus and Its Role in Neutrophilic Function
Journal of Cellular Biochemistry, 2015ABSTRACTThe cell nucleus plays a key role in differentiation processes in eukaryotic cells. It is not the nucleus in particular, but the organization of the genes and their remodeling that provides the data for the adjustments to be made according to the medium. The neutrophil nucleus has a different morphology.
Anne C.D. Neves +3 more
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Neutrophils as emerging therapeutic targets
Nature reviews. Drug discovery, 2020T. Németh, M. Sperandio, A. Mócsai
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