Results 31 to 40 of about 9,587 (206)

Triggering of Koebner Phenomenon by Picosecond Laser in a Psoriatic Patient: Clinical and Immunopathologic Insights

open access: yesLasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives To report the first case of Koebner phenomenon induced by picosecond laser treatment in a patient with psoriasis. We analyzed the clinical and histopathological features and discussed the possible mechanism by which the laser's photomechanical effect triggered the reaction.
Teppei Sakai, Koya Sonoda, Jun Omatsu
wiley   +1 more source

Effectiveness and Safety of Setmelanotide in a Patient With a Heterozygous PCSK1 Deficiency

open access: yesObesity, EarlyView.
ABSTRACT Setmelanotide, a melanocortin 4 receptor (MC4R) agonist, is a promising pharmacological treatment option for people with rare monogenic obesity conditions affecting the leptin‐melanocortin signaling pathway, including proprotein convertase subtilisin/kexin type 1 (PCSK1) gene mutations.
Ellina Lytvyak   +2 more
wiley   +1 more source

Functional validation of driver mutation‐specific uveal melanoma biomarkers: role of COL9A3 in cancer cell plasticity

open access: yesThe Journal of Pathology, EarlyView.
Abstract Uveal melanoma (UM) is a deadly ocular malignancy with well‐described genetic alterations that predict disease outcome. However, our current understanding of the biological underpinnings of high‐risk uveal melanoma progression remains relatively limited. Using RNA expression profiles from 250 patients with UM, we identified 12 novel biomarkers
QCC van den Bosch   +7 more
wiley   +1 more source

Congenital giant pigmented nevus

open access: yesJournal of Mahatma Gandhi Institute of Medical Sciences, 2014
Giant congenital pigmented nevi (
Amar Taksande, Krishna Vilhekar
doaj   +1 more source

A Prediction Model for the Differential Diagnosis of Bowen's Disease and Bowenoid Actinic Keratosis

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Bowen's disease and bowenoid actinic keratosis share overlapping clinical and histopathological features, and there is no clear consensus regarding their differential diagnosis. This study aimed to identify clinicopathological differences between the two diseases and to develop a diagnostic prediction model in a Korean population.
Byeonghyun Joo   +6 more
wiley   +1 more source

Atypical Presentation of a Pigmented Oncocytoma of the Caruncle: A Case Report

open access: yesCase Reports in Ophthalmology, 2013
We report an unusual case of a pigmented oncocytoma of the caruncle. The lesion presented the following atypical features: a well-circumscribed, partially pigmented, and lobulated mass that macroscopically resembled a caruncular nevus.
Maura Di Nicola   +5 more
doaj   +1 more source

Deep penetrating nevus: a case report and brief literature review

open access: yesDiagnostic Pathology, 2006
Background - Deep penetrating nevus (DPN) is a distinct variant of melanocytic nevus and remains a histopathologic challenge to pathologists because of its resemblance to blue nevus, malignant melanoma, pigmented Spitz nevus, and congenital melanocytic ...
Dang Linh M   +3 more
doaj   +1 more source

Basal Cell Carcinoma and Syringocystoadenoma Papilliferum Arising in Naevus Sebaceous—A Narrative Review

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Naevus sebaceous (NS) is a congenital cutaneous hamartoma characterised by epidermal, follicular, sebaceous and apocrine components, with a rare but significant potential for malignant transformation, most commonly into basal cell carcinoma (BCC).
Yajat Dua   +2 more
wiley   +1 more source

Role of amniotic membrane and full-thickness skin graft in reconstruction of kissing nevus of eyelids

open access: yesIndian Journal of Ophthalmology, 2017
A 20-year-old girl presented with a large pigmented lesion over the temporal aspect of left lateral canthus involving the lateral one-third of both eyelids, since birth. A slow increase in its size had been noticed for the past 2 years. On examination, a
Manpreet Singh   +3 more
doaj   +1 more source

Diagnostic Utility of PRAME Immunohistochemistry for Distinguishing Acral Melanoma From Acral Melanocytic Nevi

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Introduction Preferentially expressed antigen in melanoma (PRAME) immunohistochemistry helps distinguish non‐acral melanocytic lesions, but few studies have addressed its value in acral lesions. We aimed to identify an optimal PRAME cut‐off score to differentiate acral melanoma (AM) from acral melanocytic nevi (AMN).
Kritsada Phatcharamaneepakorn   +4 more
wiley   +1 more source

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