Results 41 to 50 of about 9,587 (206)

PDGFD‐Rearranged Dermatofibrosarcoma Protuberans With S100 and Pan‐TRK Expression

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Dermatofibrosarcoma protuberans (DFSP) is a fibroblastic malignancy characterized in most cases by COL1A1::PDGFB fusion. Rare cases exhibit alternative rearrangements involving PDGFD. Here, we describe a female patient in her third decade of life who presented with a spindle cell proliferation on the shoulder.
Venezia Podesta, May P. Chan, Douglas Rottmann, Kelly L. Harms, Paul W. Harms   +4 more
wiley   +1 more source

Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling

Cytopathology, EarlyView.
Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu, Mokhtar Abdelhammed, Xu Cao, Nisha S. Ramani   +3 more
wiley   +1 more source

Presentación de un paciente con diagnóstico de nevus melanocítico pigmentado congénito gigante

Correo Científico Médico, 2012
Se presenta un paciente de seis años de edad, con diagnóstico clínico de nevus melanocítico congénito gigante con el objetivo de describir el comportamiento clínico y hacer énfasis en la importancia del seguimiento de este enfermo por la posibilidad de ...
Noemí Batista Muñoz, Yorlin Céspedes Fonseca, Sonia Peregrín Rodríguez, Onelia M Hernández Marrero, Aida Marta Dager Haber   +4 more
doaj  

Afamelanotide improves quality of life and light tolerance in Austrian erythropoietic protoporphyria patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Erythropoietic protoporphyria (EPP) is a rare genetic disorder characterized by severe phototoxic reactions that occur within minutes of light exposure. In clinical studies, afamelanotide has been shown to prolong pain‐free sun exposure, improve quality of life, and reduce the frequency and severity of phototoxic reactions ...
Magdalena Seidl‐Philipp, Hanna Schratter, Johanna Auer, Gerold Schwantzer, Maximilian Lammer, Philipp Hinteregger, Ines Vergeiner, Robert Gruber, Peter Wolf, Angelika Hofer   +9 more
wiley   +1 more source

S1 guideline sweat gland carcinoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The current classification of sweat gland carcinomas is based on histomorphological characteristics and distinguishes between more than 20 entities. Most patients are older, but some subtypes also affect middle‐aged and younger patients. The majority of tumors arise de novo. Sweat gland carcinomas have nonspecific clinical features.
Mirjana Ziemer, Michael Erdmann, Abbas Agaimy, Jürgen C. Becker, Almut Böer‐Auer, Doris Helbig, Cornelia Erfurt‐Berge, Alexander Frisman, Conrad Hempel, Ulrike Leiter, Friedegund Meier, Thomas Mentzel, Lara Racz, Silke Redler, Stefan Schliep, Clemens Seidel, Alpaslan Tasdogan, Jochen Utikal, Carsten Weishaupt, Selma Ugurel   +19 more
wiley   +1 more source

Deep penetrating nevus: A distinct variant of melanocytic nevus

Indian Journal of Pathology and Microbiology, 2011
Deep penetrating nevus (DPN) is a variant of melanocytic nevus which goes unrecognized due to its relative rarity and may be misinterpreted as malignant melanoma.
Aparna Gupta, P S Srilatha, Niveditha Suvarna, Lakshmi Rao   +3 more
doaj   +1 more source

Multiclass convolutional neural network vs. 96 dermatologists in skin lesion diagnosis, an international study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Artificial intelligence was shown to improve diagnostic accuracy for skin cancer detection. While most clinically approved models provide binary “benign/malignant” classifications, multiclass predictions may offer greater clinical utility.
Katharina Susanne Kommoss, Julia Katharina Winkler, Anastasia Sophie Vollmer, Christine Mueller‐Christmann, Ferdinand Toberer, Wilhelm Stolz, Teresa Kraenke, Rainer Hofmann‐Wellenhof, Andreas Blum, Alexander Enk, Albert Rosenberger, Holger Andreas Haenssle   +11 more
wiley   +1 more source

Age‐related dermatoscopic features of excised melanomas versus nevi in 832 high risk patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Melanocytic nevi show distinct age‐related dermoscopic patterns. However, data on age‐related patterns of melanomas are lacking. This study aimed to identify age‐related static and dynamic dermoscopic patterns of melanomas. Patients and methods Explorative cross‐sectional cohort study between October 1996 and May 2012,
Jana Burghaus‐Zhang, Julia Katharina Winkler, Katharina Susanne Kommoss, Anastasia Sophie Vollmer, Alexander Enk, Timo Buhl, Holger Andreas Haenssle   +6 more
wiley   +1 more source

Proliferating Giant Pigmented Nevus: A Report of an Unusual Tumor Occurring in Association with a Congenital Giant Pigmented Nevus.

Journal of Investigative Dermatology, 1989
A 32-year-old Japanese woman with a giant pigmented congenital nevus of the torso presented with a massive pigmented tumor mass of the vulva which grew over an 8-year period. Histologically, the tumor was composed of benign appearing nevus-like cells with focal areas of extensive fibrous response.
Arao, Tatsuyoshi, Yamada, Masanobu, Matsunaga, Wakatoshi, Kageshita, Toshiro, Ono, Tomomichi   +4 more
openaire   +2 more sources

AI‐assisted diagnosis of nail unit melanoma and melanonychia using a clinical deep learning model

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Nail unit melanoma (NUM) is a rare but potentially fatal malignancy often misdiagnosed as melanonychia. Because biopsy may cause permanent nail dystrophy, accurate noninvasive diagnosis is essential. This study aimed to develop and validate an artificial intelligence model to distinguish NUM from benign melanonychia ...
Yusung Chu, Sejung Yang, Jin‐Woong Jung, Jun Young Kim, Joon‐Goon Kim, Hae June Sung, Byungho Oh   +6 more
wiley   +1 more source