Results 71 to 80 of about 306,099 (237)

A Review of Melanoma Subtypes: Genetic and Treatment Considerations

Journal of Surgical Oncology, EarlyView.
ABSTRACT Melanoma affects over one million people in the United States. This review explores genetic mutations and markers of all seven subtypes. Current treatment options and prognosis of each subtype are also discussed. For lentigo maligna, spitzoid, and nodular subtypes, BRAF was the most common mutation reported. For superficial spreading, TP53 was
Christina Druskovich, Jesse Kelley, Jason Aubrey, Leah Palladino, G. Paul Wright   +4 more
wiley   +1 more source

Role of amniotic membrane and full-thickness skin graft in reconstruction of kissing nevus of eyelids

Indian Journal of Ophthalmology, 2017
A 20-year-old girl presented with a large pigmented lesion over the temporal aspect of left lateral canthus involving the lateral one-third of both eyelids, since birth. A slow increase in its size had been noticed for the past 2 years. On examination, a
Manpreet Singh, Natasha Gautam, Manpreet Kaur, Zoramthara Zadeng   +3 more
doaj   +1 more source

Skin Diseases in Long‐Distance Runners

JEADV Clinical Practice, EarlyView.
ABSTRACT Long‐distance running, including both road running and trail/mountain running, has significantly increased in popularity in recent years. The prolonged, repetitive physical activity combined with environmental exposures predisposes runners to a range of dermatological problems.
Henna Ahomies, Vincent Descamps, Stéphanie Leclerc‐Mercier, Nicolas Kluger   +3 more
wiley   +1 more source

Clinical patterns of vitiligo in Japan: A descriptive study using the JMDC claims database

The Journal of Dermatology, EarlyView.
Abstract Vitiligo is a chronic autoimmune disorder that profoundly impacts patients' quality of life. Real‐world data on vitiligo in Japan are limited. This descriptive, cross‐sectional study used a claims database to evaluate vitiligo prevalence, patient demographics, treatments, and comorbidities in Japanese patients with vitiligo.
Atsushi Tanemura, Yue Ma, Masayo Sakaki‐Yumoto, Shintaro Hiro, Tomohiro Hirose, Tamio Suzuki   +5 more
wiley   +1 more source

Becker′s nevus with neurofibromatosis type 1

Annals of Indian Academy of Neurology, 2015
Neurofibromatosis type 1 is an autosomal dominant disorder which primarily affects the growth and development of neural cell tissues. It presents as multiple tumor-like growths over the skin that arises from the nerves and is associated with other ...
Sumit Kar, Krishnan Preetha, Nidhi Yadav, Bhushan Madke, Nitin Gangane   +4 more
doaj   +1 more source

FT-Raman spectroscopy for the differentiation between cutaneous melanoma and pigmented nevus.

Acta Cirurgica Brasileira, 2010
UNLABELLED Cutaneous melanoma is the most aggressive type of skin cancer and Ft-Raman spectroscopy has been studied as a potential method that could be a real alternative for early diagnosis of neoplasms.
S. Cartaxo, I. Santos, R. Bitar, A. Oliveira, L. Ferreira, H. Martinho, A. Martin   +6 more
semanticscholar   +1 more source

IMPDH2's Central Role in Cellular Growth and Diseases: A Potential Therapeutic Target

Cell Proliferation, EarlyView.
IMPDH2 is a rate‐limiting enzyme in guanine nucleotide biosynthesis. It plays diverse roles in various physiological and pathological processes: nucleotide metabolism, inflammation, immune function, ribosomal stress. Structural or regulatory alterations in IMPDH2 are linked to significant health issues, and critical relevance in disease progression. We
Zheng Li, Yunpeng Zou, Jiayao Niu, Ying Zhang, Aohua Yang, Wenyu Lin, Jie Guo, Shuya Wang, Ronghan Liu   +8 more
wiley   +1 more source

Deep penetrating nevus: A distinct variant of melanocytic nevus

Indian Journal of Pathology and Microbiology, 2011
Deep penetrating nevus (DPN) is a variant of melanocytic nevus which goes unrecognized due to its relative rarity and may be misinterpreted as malignant melanoma.
Aparna Gupta, P S Srilatha, Niveditha Suvarna, Lakshmi Rao   +3 more
doaj   +1 more source

A new channel for excitonic transport in the FMO complex [PDF]

arXiv, 2021
We expose a new excitation transport channel in FMO, consisting of the 7 intramonomeric pigments and their 2nd nearest intermonomeric counterpart. Such a channel outcompetes the standard alternative, where intramonomeric pigments partner with their closest intermonomeric pigment.
arxiv  

The Prognostic Significance of Tumoral Melanosis

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Tumoral melanosis (TM) is a histological term to describe a nodular aggregation of macrophages containing melanin pigment (melanophages) that is devoid of viable melanocytes. It is most often identified in skin, where it may be appreciated clinically as a pigmented lesion; however, it can also be found in other organs such as lymph ...
Alison J. Potter, Peter M. Ferguson, Serigne N. Lo, Tasnia Ahmed, Robert V. Rawson, John F. Thompson, Georgina V. Long, Richard A. Scolyer   +7 more
wiley   +1 more source