Results 171 to 180 of about 26,695,458 (198)
New approach methodologies (NAMs) to study microbiome–host interactions
Current Opinion in Toxicology, 2023 Gut microbiota plays an important role in host health and disease. They metabolize food-born chemicals, nutrients, drugs and other xenobiotics, while these chemicals and their metabolites can also modulate the gut microbiota. The present review provided an overview of the state-of-the-art in the application of in vitro and in silico based new approach ...
Ivonne M. C. M. Rietjens
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New Approach Methodologies (NAMs) for Carcinogenicity Evaluation
Toxicologic PathologyThe second session of the 2nd Joint BSTP/ESTP Toxicologic Pathology Congress, Manchester, UK, September 23-26, 2025, entitled “New Approach Methodologies for Carcinogenicity Evaluation,” was dedicated to innovative strategies for assessing carcinogenic risks in various substances, particularly in drug development and agrochemicals.
Frederic Schorsch +5 more
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New Approach Methodologies (NAMs) Training Pilot Program
2023Poster to WC12 in August 27-31, 2023 in Niagara Falls, CanadaScience Inventory, CCTE products: https://cfpub.epa.gov/si/si_public_search_results.cfm?advSearch=true&showCriteria=2&keyword=CCTE&TIMSType=&TIMSSubTypeID=&epaNumber=&ombCat=Any&dateBeginPublishedPresented=07/01/2017&dateEndPublishedPresented=& ...
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New Approach Methodologies (NAMs) for safety testing of complex food matrices
Trends in Food Science and Technology, 2023Background: The conventional toxicological approach which primarily relies on animal testing has undergone several transformations in recent years due to limitations in translational relevance, ethical and reproducibility concerns, high costs, and time-consuming procedures.
Manful, Maame Ekua +2 more
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New Approach Methodologies (NAMs) and Chemical Risk Assessment
2020Presentation given to the Georgetown Univ Environmental Health Risk Assessment Class April 24 ...
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2021
Presentation to the EPA Developmental Neurotoxicology DNT Journal Club June 2021Search for CCTE records in EPA’s Science Inventory by typing in the title at this link.https://cfpub.epa.gov/si/si_public_search_results.cfm?advSearch=true&showCriteria=2&keyword=CCTE&TIMSType=&TIMSSubTypeID=&epaNumber=&ombCat=Any& ...
Carstens, Kelly +5 more
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Presentation to the EPA Developmental Neurotoxicology DNT Journal Club June 2021Search for CCTE records in EPA’s Science Inventory by typing in the title at this link.https://cfpub.epa.gov/si/si_public_search_results.cfm?advSearch=true&showCriteria=2&keyword=CCTE&TIMSType=&TIMSSubTypeID=&epaNumber=&ombCat=Any& ...
Carstens, Kelly +5 more
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New approach methodologies (NAMs) in drug safety assessment: A vision of the future
Current Opinion in ToxicologyRuth A Roberts
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Regulatory Toxicology and Pharmacology, 2020
Nonclinical testing of human pharmaceuticals is conducted to assess the safety of compounds to be studied in human clinical trials and for marketing of new drugs. Although there is no exact number and type of nonclinical studies required for safety assessments, as there is inherent flexibility for each new compound, the traditional approach is outlined
Amy M, Avila +18 more
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Nonclinical testing of human pharmaceuticals is conducted to assess the safety of compounds to be studied in human clinical trials and for marketing of new drugs. Although there is no exact number and type of nonclinical studies required for safety assessments, as there is inherent flexibility for each new compound, the traditional approach is outlined
Amy M, Avila +18 more
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Assessment of Chemicals, Using and Developing New Approach Methodologies (NAMs)
2018Presentation to the Advancing the Pace of Chemical Risk Assessment (APCRA) Case Study working meeting held October ...
Sobanski, Tomasz +3 more
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Use of Computational New Approach Methodologies (NAMs) in Human Exposure Modelling
2023Presentation to SOT on March 10-14, 2024 in Salt Lake City, UtahScience Inventory, CCTE products: https://cfpub.epa.gov/si/si_public_search_results.cfm?advSearch=true&showCriteria=2&keyword=CCTE&TIMSType=&TIMSSubTypeID=&epaNumber=&ombCat=Any&dateBeginPublishedPresented=07/01/2017&dateEndPublishedPresented=& ...
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