Results 181 to 190 of about 26,695,458 (198)

A Cheminformatics Workflow to Select Representative TSCA Chemicals for New Approach Methodology (NAM) Screening

Chemical Research in Toxicology
Presentation to SOT on March 10-14, 2024 in Salt Lake City, UtahSearch for CCTE records in EPA’s Science Inventory by typing in the title at this link. https://cfpub.epa.gov/si/si_public_search_results.cfm?advSearch=true&showCriteria=2&keyword=CCTE&TIMSType=&TIMSSubTypeID=&epaNumber=&ombCat=Any&dateBeginPublishedPresented=07/
Grace Patlewicz, Antony J. Williams, Matthew Adams, Imran Shah, Katie Paul-Friedman   +4 more
openaire   +2 more sources

Advancing New Approach Methodologies (NAMs) through the publication of negative results

Alternatives to Laboratory Animals
The non-publication of negative or null results contributes to increased animal use in biomedical research and experimentation, by encouraging the unnecessary repetition of studies. This practice also delays the development, validation and uptake of alternative methods, including New Approach Methodologies (NAMs). This
Cristiane Caldeira, Carolina de Oliveira, Octavio Presgrave   +2 more
openaire   +1 more source

A CDER perspective: Landscape of New Approach Methodologies (NAMs) submitted in drug development programs

Regulatory Toxicology and Pharmacology
This study analyzes the landscape of studies using New Approach Methodologies (NAMs) and submitted to the FDA over the past 15 years. The study utilized a custom-developed Center for Drug Evaluation and Research (CDER) search tool to examine keywords in Module 4 of the Electronic Common Technical Document (eCTD) across various drug applications.
Tyna Dao, Nakissa Sadrieh
openaire   +2 more sources

Availability of New Approach Methodologies (NAMs) in the Endocrine Disruptor Screening Program (EDSP)

2023
Presentation to the Physicians Committee for Responsible Medicine (PCRM) DyNAMic Discussions Webinar Series April 2023 Search for CCTE records in EPA’s Science Inventory by typing in the title at this link. https://cfpub.epa.gov/si/si_public_search_results.cfm?advSearch=true&showCriteria=2&keyword=CCTE&TIMSType=&TIMSSubTypeID=& ...
openaire   +1 more source

The role of ‘big data’ and ‘ New Approach Methodologies (NAMs) in ending animal use – A commentary on progress

Computational Toxicology, 2022
Timothy E H Allen, Domenico Gadaleta
exaly  

Reference Chemical Potency List (RCPL): A new tool for evaluating the accuracy of skin sensitisation potency measurements by New Approach Methodologies (NAMs)

Regulatory Toxicology and Pharmacology, 2022
Amaia Irizar, Peter Griem
exaly  

Chemical Testing Using New Approach Methodologies (NAMs)

2022
openaire   +1 more source

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Frontiers in Toxicology, 2022
exaly  

New approach methodologies (NAMs) for drug-induced liver injury (DILI): Where are we now?

Drug Discovery Today
Minjun Chen, Dongying Li, Weida Tong
exaly  

Assessment of endocrine disruptors in the European Union: Current regulatory framework, use of new approach methodologies (NAMs) and recommendations for improvements

Regulatory Toxicology and Pharmacology
Terje Svingen, Nora Bouftas
exaly