Results 111 to 120 of about 20,567,251 (318)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Embedding Diversity: Communication and Label Concept for Underutilized Crops – Checklist for your First Evaluation [PDF]
, 2018 There are some very successful cases of marketing of underutilized crops in European countries. Examples are the marketing of rare varieties in Austrian and Swiss supermarkets.
Förster, Iris +2 more
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
New Evapotranspiration Crop Coefficients [PDF]
Journal of the Irrigation and Drainage Division, 1982 Improved crop coefficients for various Pacific Northwest irrigated crops were developed for estimating crop evapotranspiration (ET) from estimates or measurements of reference ET. Reference ET was based on that for well watered, actively growing alfalfa with sufficient growth for near maximum ET in arid, irrigated regions.
openaire +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Finding Missing Markets (and a disturbing epilogue): Evidence from an Export Crop Adoption and Marketing Intervention in Kenya [PDF]
In much of the developing world, many farmers grow crops for local or personal consumption despite export options which appear to be more profitable. Thus many conjecture that one or several markets are missing.
Dean Karlan, Nava Ashraf, Xavier Giné
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Settlement of South Carolina’s Colonial Backcountry: From Conflict to Prosperity [PDF]
, 2016 The Carolina Colony was the first foothold for the British in the lower south region of North America. Carolina developed in the tradition of Barbados, with its economy based on staple crops. These staple crops would become rice and indigo, both of which
Pruitt, Steven C.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
A Draft Genome Resource for a Cacao Thread Blight Disease–Causing Strain of Paramarasmius palmivorus
PhytoFrontiersThread blight disease (TBD) is an emerging foliar disease on cacao (Theobroma cacao), the source of chocolate. Multiple species of pathogenic fungi in the Marasmiinae suborder of Agaricales are responsible for causing TBD in cacao.
Indrani K. Baruah +5 more
doaj +1 more source