Results 141 to 150 of about 20,567,251 (318)

Technology Adoption, Management Practices, and Financial Performance of New and Beginning Farmers: Evidence from a National Survey [PDF]

open access: yes
More than 50 percent of current farmers are over age 55, and the number of new farmers replacing them has fallen. This paper examines factors that contribute to the financial performance of new and beginning farmers in the U.S.
Mishra, Ashok K.   +2 more
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Low soil pH enhances fruit acidity by inhibiting citric acid degradation in lemon (Citrus lemon L.)

open access: yesHorticulture Advances
Fruit acidity significantly influences fruit flavor, but the specific impact of soil pH on fruit acidity remains unclear. This study investigated the effects of various soil pH levels on fruit acidity and citric acid (CA) metabolism in lemon (Citrus ...
Songwei Wu   +7 more
doaj   +1 more source

Fine mapping and identification of CaTTG1, a candidate gene that regulates the hypocotyl anthocyanin accumulation in Capsicum annuum

open access: yesHorticultural Plant Journal
Pepper (Capsicum annuum L.) is a typical self-pollinating crop with obvious heterosis in hybrids. Consequently, the use of morphological markers during the pepper seedling stage is crucial for pepper breeding.
Jin Wang   +11 more
doaj   +1 more source

Modelling Possible Impacts of GM Crops on Australian Trade [PDF]

open access: yes
This paper looks at the impact on Australia’s trade in crops (non-wheat grains and oilseeds) where GM technology has been introduced. The model includes assumptions about the productivity gains of GM crops, possible consumer responses and regulatory ...
, , Susan Stone
core  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Integrated transcriptome and metabolome analysis reveals anthocyanin biosynthesis mechanisms in pepper (Capsicum annuum L.) leaves under continuous blue light irradiation

open access: yesBMC Plant Biology
Background Different metabolic compounds give pepper leaves and fruits their diverse colors. Anthocyanin accumulation is the main cause of the purple color of pepper leaves.
Yao Zhou   +7 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

THE ECONOMIC EFFECTS OF IRRIGATION AND DUNGING IN THE SUGAR-BEET PRODUCTION

open access: yesEkonomika Poljoprivrede (1979), 2010
The research of production and economic effects of irrigation to the sugarbeet and sugar growth per hectare was carried out on the carbonate humus of favourable water-physical and chemical characteristics on the location of Rimski Šančevi during the ...
Livija Maksimović   +3 more
doaj  

Spatial Efficiency Analysis of Arable Crops in Greece [PDF]

open access: yes
This paper aims at the analysis of determinants of efficiency of arable crops in a spatial context in Greece. Moreover it suggests policy interventions in order to diminish regional inequalities in efficiency and to raise the average level of efficiency,
Anastassios Karaganis   +1 more
core  

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