Results 61 to 70 of about 19,296,157 (316)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
TOWARD QUEER POTENTIALITIES IN CHILD AND YOUTH CARE
International Journal of Child, Youth & Family Studies, 2021 Arguably, from the invention of adolescence at the beginning of the 20th century, developmental theory has served as the foundation of disciplinary study and professional practice with children and youth across the global West.
Bobbi Ali Zaman, Ben Anderson-Nathe
doaj +1 more source
Rethinking agency: developmentalism, gender and rights [PDF]
, 2013 In a new book, LSE’s Sumi Madhok proposes a new theoretical framework for agency thinking by examining the ethical, discursive and practical engagements of a group of women development workers in north-west India with developmentalism and individual ...
Madhok, Sumi, South Asia, LSE
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Toward a global coal mining moratorium? A comparative analysis of coal mining policies in the USA, China, India and Australia [PDF]
, 2018 To stop global warming at well below 2° C, the bulk of the world’s fossil fuel reserves will have to be left in the ground. Coal is the fossil fuel with the greatest proportion that cannot be used, and various advocacy groups are campaigning for a ban on
Blondeel, Mathieu, Van de Graaf, Thijs
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Novo desenvolvimentismo e liberalismo enraizado New developmentalism and embedded liberalism
Serviço Social & Sociedade, 2012 O objetivo geral deste artigo é discutir a evolução da formulação político‑ideológica de desenvolvimento econômico conhecida como novo desenvolvimentismo.
Reinaldo Gonçalves
doaj +1 more source
A new paradigm for developmental biology [PDF]
Journal of Experimental Biology, 2007 SUMMARYIt is usually thought that the development of complex organisms is controlled by protein regulatory factors and morphogenetic signals exchanged between cells and differentiating tissues during ontogeny. However, it is now evident that the majority of all animal genomes is transcribed, apparently in a developmentally regulated manner, suggesting ...
openaire +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Reflections on the old and new developmentalism
Brazilian Journal of Political Economy, 2018 New Developmentalism provides a view out how it incorporates the positive contributions of early development theorists concerned with to the past of development theory as well as a view to the future.
JAN KREGEL
doaj +1 more source