Results 71 to 80 of about 515,250 (294)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Hide and seek: how PDFs can conceal new physics

Journal of High Energy Physics, 2023
The interpretation of LHC data, and the assessment of possible hints of new physics, require the precise knowledge of the proton structure in terms of parton distribution functions (PDFs). We present a systematic methodology designed to determine whether
Elie Hammou, Zahari Kassabov, Maeve Madigan, Michelangelo L. Mangano, Luca Mantani, James Moore, Manuel Morales Alvarado, Maria Ubiali   +7 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Baryonic dark forces in electron-beam fixed-target experiments

Journal of High Energy Physics
New GeV-scale dark forces coupling predominantly to quarks offer novel signatures that can be produced directly and searched for at high-luminosity colliders. We compute the photon-proton and electron-proton cross sections for producing a GeV-scale gauge
Safa Ben Othman, Armita Jalooli, Sean Tulin   +2 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Constraints on photon mass and dark photon from the Jovian magnetic field

Journal of High Energy Physics
The Jovian magnetic field, being the strongest and largest planetary one in the solar system, could offer us new insights into possible microscopic scale new physics, such as a non-zero mass of the Standard Model (SM) photon or a light dark photon ...
Shi Yan, Lingfeng Li, JiJi Fan
doaj   +1 more source

Combined constraints on dark photons and discovery prospects at the LHC and the Forward Physics Facility

Journal of High Energy Physics, 2023
Hidden sectors are ubiquitous in supergravity theories, in strings and in branes. Well motivated models such as the Stueckelberg hidden sector model could provide a candidate for dark matter.
Amin Aboubrahim, Mohammad Mahdi Altakach, Michael Klasen, Pran Nath, Zhu-Yao Wang   +4 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Searching for string bosenovas with gravitational wave detectors

Journal of High Energy Physics
We study the phenomenology of a string bosenova explosion in vector superradiance clouds around spinning black holes, focusing on the observable consequences in gravitational wave detectors and accelerometers.
Dawid Brzeminski, Anson Hook, Junwu Huang, Clayton Ristow   +3 more
doaj   +1 more source