Results 131 to 140 of about 18,947,439 (256)
Topic Modeling for Humanities Research
, 2013 Topic Modeling for Humanities Research, a one-day workshop directed by Assistant Director of MITH Dr. Jennifer Guiliano, received a Level 1 Digital Humanities start up from the National Endowment for the Humanities on April 19, 2011.
Maryland Institute for Technology in the Humanities +1 more
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Utah Humanities Research Foundation correspondence, 1950-1952
, 1947 A set of letters dated 1947 to 1950 related to the work of the Utah Humanities Research Foundation, particularly the publication of articles in the Utah Humanities Review and Western Humanities Review.
Utah Humanities Research Foundation; Lee, Hector, 1908-1992; Bentley, Harold W.; Folland, Harold F.; Mulder, William
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Humanities, Vol. 13, Num. 5, September/October 1992
, 1992 Featured story: Chairman's Report: The State of Humanities in Higher ...
National Endowment for the Humanities, Office of Publications
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Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Knowledge networks in the humanities
, 2014 In settings where digital humanities thrive, there are common ingredients, including strong structures for collaboration, frameworks for interdisciplinary dialogue, spaces for experimentation, and mechanisms for institutionally valuing and sustaining ...
Arthur, Paul Longley (R17536)
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source