Results 131 to 140 of about 126,433 (311)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Introduction: Digital humanities
Mètode Science Studies Journal: Annual ReviewOver the past thirty years, a new discipline has been slowly but surely gaining ground in the humanities. It has come to be known as the digital humanities.
Teresa Ferrer Valls
doaj +1 more source
Introduction: Why Cartographic Humanities?
The humanities have been part of geographical knowledge and its expression for centuries, finding in maps and cartographic imaginations useful and intimate companions to reflect with, challenge and advance new spatial paradigms, methods and metaphors ...
Rossetto, Tania, Lo Presti, Laura
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Cloud computing and the humanities: National eResearch Collaboration Tools and Resources [PDF]
, 2012 The NeCTAR Research Cloud provides free cloud computing for Australian Researchers. This poster describes this important piece of new infrastructure, and why those in the digital humanities might be interested.Australian Academy of the Humanities; the ...
Fifield, Tom
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
New Paths to Spatial Expression from a Digital Humanities Perspective
Redai diliIn the context of the digital age, digital humanities has evolved into a cutting-edge interdisciplinary field that deeply integrates computational and humanistic thinking, representing a fundamental shift in research paradigms driven by data, employing ...
Zhuang Liang, Ye Chao
doaj +1 more source
Humanities Center Flipbook 2024-25
Table of Contents: Welcome Meet the Fellows The New Humanities Center small Talks Humanities Center Co-Sponsored Event/Activity Grants Faculty-Student Enrichment Grants Faculty Project Grants Faculty Speakers Conference Travel Research Support ...
Humanities Center,
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source