Results 111 to 120 of about 18,678,968 (349)

Ecofeminist Echoes in New Materialism?

open access: yes, 2016
Do ecofeminism and new materialism share common features? In ecofeminist literature’s concern for the nonhuman, one could foresee feminist theory’s “material turn” that would eventually lead to new materialist feminisms.
CASSELOT, MARIE-ANNE
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Rights of Nature: Considering Conatus Essendi from the Perspective of New Materialism

open access: yesRetorik: Jurnal Ilmu Humaniora
This study examines the concept of natural rights through the lens of discourse analysis, focusing on how Baruch Spinoza’s idea of conatus essendi is reinterpreted within the framework of new materialism.
Eventus Ombri Kaho
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

New materialism: interviews & cartographies [PDF]

open access: yes, 2017
Reseña del libro: Rick Dolphijn and Iris van der Tuin, "New Materialism: Interviews & Cartographies" (Ann Arbor, MI: Open Humanities Press, 2012), 197 ...
Hall, Molly Volanth
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Publication: New Issue of Anthropology&Materialism "Discontinuous Infinities. Walter Benjamin and Philosophy"

open access: yes, 2017
We are happy to announce the publication of Discontinuous Infinities, a special issue of the online journal Anthropology & Materialism, dedicated to the philosophy of Walter Benjamin. The issue, co-edited by Jan Sieber and Sebastian Truskolaski, features
Jan Sieber
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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