Results 111 to 120 of about 154,707 (297)

Reflection, Intelligibility, and Leibniz’s Case Against Materialism [PDF]

open access: yes, 2018
Leibniz’s claim that it is possible for us to gain metaphysical knowledge through reflection on the self has intrigued many commentators, but it has also often been criticized as flawed or unintelligible.
Borcherding, Julia
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

ECOHUMAN IN NEW MATERIALIST HUMANISM: “ENERGY AND CHANGE” BY CLAYTON CROCKETT

open access: yesGlocalism: Journal of Culture, Politics and Innovation
This commentary to Clayton Crockett’s Energy and Change: A New Materialist Cosmology details his use of systems concepts as it extends his energy framework to conceive of the ecohuman, a new concept that broadens anthropocentric and humanist traditions ...
ROBERT DRURY KING
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Process of individuation in hybrid ecologies: on the relationship between art, machines and natural systems

open access: yesArtnodes
The following article proposes a relational techno-aesthetics (Simondon-Stiegler) and an onto-epistemological (Barad-Bergson) perspective of technical objects, in order to conceive them as processes of dynamic relations, open and entangled relations ...
Renzo Filinich, Daniela Cespedes
doaj   +1 more source

Nature, Science, Bayes' Theorem, and the Whole of Reality [PDF]

open access: yes, 2015
A fundamental problem in science is how to make logical inferences from scientific data. Mere data does not suffice since additional information is necessary to select a domain of models or hypotheses and thus determine the likelihood of each model or ...
Alexanian, Moorad
core  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Marx on Historical Materialism [PDF]

open access: yes, 2017
Marx’s theory of historical materialism seeks to explain human history and development on the basis of the material conditions underlying all human existence. For Marx, the most important of all human activities is the activity of production by means of
Baur, Michael
core  

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

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