Results 101 to 110 of about 154,707 (297)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
The Challenging Middle of New Materialism and Intersectionality
Kvinder, Køn & ForskningA book Review of New Materialism and Intersectionality: Making Middles Matter. Edited by Katve-Kaisa Kontturi, Taru Leppänen, Tara Mehrabi & Milla Tiainen.
Cathrine Bjørnholt Michaelsen
doaj +1 more source
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Critique [of Cultural Differences in American and Southeast Asian Children\u27s Psychosocial Development by Jacqueline Ulmen Zbaracki] [PDF]
, 1985 Zbaracki\u27s thought provoking discussion suggests one way in which the Southeast Asian, now American, community can enhance our understanding of a world view entirely different from our own and the ways in which it is taught.
Deck, Alice
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
, 2002 In his day, Joseph Priestley (1733-1804) was a philosopher of some importance. He argued the case for materialism perhaps more cogently than did any British thinker before recent times.
Tapper, Alan
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Unknowing to Know More about Sexuality Education
Gender a Výzkum, 2022 Review of book Allen, L.
Handan Titiz Ceritoglu
doaj
A Defence of Cartesian Materialism [PDF]
, 1999 One of the principal tasks Dennett sets himself in "Consciousness Explained" is to demolish the Cartesian theatre model of phenomenal consciousness, which in its contemporary garb takes the form of Cartesian materialism: the idea that conscious ...
O'Brien, Gerard, Opie, Jon
core
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source