Results 81 to 90 of about 18,869,389 (279)
From New Materialism to the Postdigital: Religious Responses to Environment and Technology. [PDF]
Postdigit Sci Educ, 2021 Reader J.
europepmc +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Rights of Nature: Considering Conatus Essendi from the Perspective of New Materialism
Retorik: Jurnal Ilmu HumanioraThis study examines the concept of natural rights through the lens of discourse analysis, focusing on how Baruch Spinoza’s idea of conatus essendi is reinterpreted within the framework of new materialism.
Eventus Ombri Kaho
doaj +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Tracing patterns in entangled worlds: Developing New-Hermetic Materialism for educational research
Educational FuturesThis paper proposes New-Hermetic Materialism (NHM) as a conceptual orientation for educational research, emerging from doctoral work in early childhood studies.
Kate Dudley
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Historical Materialism Conference Posters, London 2012-2022
Historical Materialism logo and London conference ...
Mabb, David
core +4 more sources
Disability Studies Quarterly, 2018 In advancing inclusion efforts this critical position paper makes explicit the relevance of new materialism as a pedagogy to counter the dominant medicalized models in Canadian and Australian school and community contexts.
Sarah Reddington, Deborah Price
doaj +1 more source