Results 91 to 100 of about 154,707 (297)

Positive associations between consumerism and tobacco and alcohol use in early adolescence: cross-sectional study [PDF]

open access: yes, 2012
<p>Background: There is concern about the negative impact of modern consumer culture on young people's mental health, but very few studies have investigated associations with substance use.
Bhaskar, A., Hunt, K., Sweeting, H.N.
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Alcune considerazioni sul rapporto tra semantica e metafisica nella teoria degli eventi di Kim [PDF]

open access: yes, 2017
La teoria degli eventi che Kim delinea \ue8 considerata una delle pi\uf9 influenti teorie metafisiche de- gli eventi. In questo lavoro si presenta tale teoria e si esamina la sua plausibilit\ue0.
Baratella, Riccardo
core   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Searching for Methodology: Feminist Relational Materialism and the Teacher-Student Writing Conference [PDF]

open access: yes, 2013
Using feminist relational materialism as a theoretical map, this paper seeks to reimage traditional case study methodology through the use of diffractive methodology.
Larson, Mindy Legard   +1 more
core   +4 more sources

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Pedagogy of New Materialism: Advancing the Educational Inclusion Agenda for Children and Youth with Disabilities

open access: yesDisability Studies Quarterly, 2018
In advancing inclusion efforts this critical position paper makes explicit the relevance of new materialism as a pedagogy to counter the dominant medicalized models in Canadian and Australian school and community contexts.
Sarah Reddington, Deborah Price
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

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