Results 91 to 100 of about 6,314,191 (290)

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

open access: yesFEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon   +5 more
wiley   +1 more source

Fall 2010 Visiting Artists Series [PDF]

open access: yes, 2010
Summary of program requiring funding (title; featured artist(s); speaker(s); scheduled date(s): The New Media and Intermedia MFA Programs are requesting funds to help support a fall lecture series.
Department of New Media and Intermedia MFA
core   +1 more source

PREPARE-Playback RatE and Priority Adaptive BitRate Selection

open access: yesIEEE Access, 2019
HAS (HTTP-based Adaptive Streaming) based on ABR (Adaptive Bitrate Rate selection) has become a prevalent solution to media transmission. In order to improve the performance of HAS, many studies focus on how to reduce the unfairness, the instability and ...
Ruixing Song   +3 more
doaj   +1 more source

News Media Brand Equity in a New Media Environment

open access: yesEconomics and Business, 2022
Abstract Digitalisation has profoundly altered how media are distributed and audiences consume media information, reshaping the media environment and introducing new competitors to media brands. This new media environment deludes media brand associations, contributing to an environment where audiences care less about content sources or ...
openaire   +2 more sources

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

open access: yesFEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner   +7 more
wiley   +1 more source

New Media Art/ New Funding Models [PDF]

open access: yes, 2000
Investigates the current state of funding for new media artists, with an emphasis on the support structures for innovative creative work that utilizes advanced technologies as the main vehicle for artistic ...
Pamela Jennings
core  

From idle to interaction – assessing social dynamics and unanticipated conversations between social robots and residents with mild cognitive impairment in a nursing home

open access: yesi-com
This paper examines the potential impact of social robots on people with mild cognitive impairments in a nursing home. Within a 4-month design case study, we investigated the practices, attitudes, and social contexts of residents with mild cognitive ...
Manavi Mehrbod   +6 more
doaj   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Auto-regulating New Media [PDF]

open access: yes, 2001
Using Foucault's (1977, 1978) notion of panoptic method of governmentality and looking at the case of Singapore's Internet policy, this paper attempts to expand on the idea-and ideals-of 'auto-regulation'(Lee, 2000, pp. 4-5; Lee & Birch, 2000).
Lee, T.
core   +1 more source

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