Community-Informed New Media-Based Knowledge Translation Addressing HIV Stigma Among the General Population and Health Care Providers in Louisville, Kentucky: A Clinical Brief. [PDF]
Nzama N +13 more
europepmc +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Social withdrawal subtypes and psychological well-being in Chinese emerging and early adults: unsociability as a protective factor and age-differentiated effects in a new media social environment. [PDF]
Kishimoto T, Wang T, Bai Q.
europepmc +1 more source
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
The Influence of New Media Literacy on Brand Engagement: Mediating Effects of Perceived Interactivity and Openness and the Moderating Effect of Age. [PDF]
Song C, Kim E.
europepmc +1 more source
Retracted: The Characteristics and Paths of the Dissemination of Intangible Cultural Heritage in the Form of Animation in the New Media Environment. [PDF]
Environmental And Public Health JO.
europepmc +1 more source
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Artificial intelligence-assisted psychological intervention mechanisms for university students in the context of new media technologies: an analysis based on data from the national institute of mental health. [PDF]
Hao N, Chen M, Zhao N, Zhang J, Zheng F.
europepmc +1 more source
Retracted: Visual Communication Design Model for New Media and Public Health Environment and New Communication Mode. [PDF]
Environmental And Public Health JO.
europepmc +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source

