Results 91 to 100 of about 6,314,191 (290)
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon+5 more
wiley +1 more source
Fall 2010 Visiting Artists Series [PDF]
Summary of program requiring funding (title; featured artist(s); speaker(s); scheduled date(s): The New Media and Intermedia MFA Programs are requesting funds to help support a fall lecture series.
Department of New Media and Intermedia MFA
core +1 more source
PREPARE-Playback RatE and Priority Adaptive BitRate Selection
HAS (HTTP-based Adaptive Streaming) based on ABR (Adaptive Bitrate Rate selection) has become a prevalent solution to media transmission. In order to improve the performance of HAS, many studies focus on how to reduce the unfairness, the instability and ...
Ruixing Song+3 more
doaj +1 more source
News Media Brand Equity in a New Media Environment
Abstract Digitalisation has profoundly altered how media are distributed and audiences consume media information, reshaping the media environment and introducing new competitors to media brands. This new media environment deludes media brand associations, contributing to an environment where audiences care less about content sources or ...
openaire +2 more sources
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner+7 more
wiley +1 more source
New Media Art/ New Funding Models [PDF]
Investigates the current state of funding for new media artists, with an emphasis on the support structures for innovative creative work that utilizes advanced technologies as the main vehicle for artistic ...
Pamela Jennings
core
This paper examines the potential impact of social robots on people with mild cognitive impairments in a nursing home. Within a 4-month design case study, we investigated the practices, attitudes, and social contexts of residents with mild cognitive ...
Manavi Mehrbod+6 more
doaj +1 more source
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp+5 more
wiley +1 more source
Auto-regulating New Media [PDF]
Using Foucault's (1977, 1978) notion of panoptic method of governmentality and looking at the case of Singapore's Internet policy, this paper attempts to expand on the idea-and ideals-of 'auto-regulation'(Lee, 2000, pp. 4-5; Lee & Birch, 2000).
Lee, T.
core +1 more source