Results 111 to 120 of about 2,339,823 (316)
New Beginnings Contact and Social Media Plugs Leaflet
, 2017 Leaflet listing all of New Beginnings contact information, including their social media and warning signs of domestic ...
New Beginnings
core
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Exploring the theme of the putative transformation of political modernity under the impact of "new" media, this book adopts a questioning approach to the ways in which cultural and technological factors are affecting the temper of political life, and ...
Axford, Barrie., Huggins, Richard.
core
Key Issues and Approaches to Media Studies Mod 1 Unit 6
, 2010 This module introduces a variety of influential, competing ways of thinking about the media within the broad area of social science research, but drawing also on other disciplines.
Department of Media and Communications
core
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Swedish politicians and new media: Democracy, identity and populism in a digital discourse
, 2014 The empirical material of this article consists of interviews with politicians in Västerbotten, an area in the north of Sweden. The aim of the article is to identify and analyse how these politicians relate to digital information technology and new media.
Bo Nilsson +3 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Working the algorithm: Contextual skills of on-demand gig workers
Big Data & SocietyThis study explores the algorithmic skills of on-demand gig workers, such as food delivery workers and ride-hailing drivers, who navigate algorithmic management on a daily basis. While algorithms often constrain worker autonomy and reduce labor processes
Xinyi Hong, Xinyi Cheng, Dong Liu
doaj +1 more source