Results 131 to 140 of about 2,339,823 (316)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

The Critical Role and Effects of Patient-Centered Communication in Psychotherapy: A Narrative Review

Psychology Research and Behavior Management
Yaohong Niu,1,* Jingbo Sun,2,* Kerun Zhu,1 Bojun Xu,1 Yin-Ping Zhang,3 Min Peng3 1School of Journalism and New Media, Xi’an Jiaotong University, Xi’an, 710049, People’s Republic of China; 2School of Sport Management and Communication ...
Niu Y, Sun J, Zhu K, Xu B, Zhang YP, Peng M   +5 more
doaj  

Mediating Hope: New Media, Politics and Resistance

, 2008
In an attempt to reimagine the concept of resistance in media studies this article argues for a reconsideration of the concept of political hope in non-mainstream mediated political mobilization that will take us beyond a focus on resistance to one of ...
Fenton, Natalie, Natalie Fenton
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

New Media Department Spring Lecture Series

, 2010
The New Media Department and the Intermedia MFA Program are requesting funds to help support our Spring lecture series. All of the visiting artists and researchers proposed in our lecture series will publicly share their expertise in the following areas:
Department of New Media
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Aotearoa New Zealand Media Ownership 2024

This report is part of JMAD’s ongoing series on Aotearoa New Zealand media ownership. Since 2011, the AUT research centre for Journalism, Media and Democracy (JMAD) has published reports that document and analyse developments within Aotearoa New Zealand ...
Hope, Wayne, Hoar, Peter, McEwan, Rufus, Baker, Sarah, Te, Saing, Middleton, Atakohu, Selman Julian, Dannie, Treadwell, Greg   +7 more
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

New Media : An Introduction

, 2005
New Media: An Introduction 2e looks at the forces shaping new media technologies, and their social, cultural, political and economic impacts. It approaches the new media as social and cultural forms that are transforming everything from commerce to ...
Flew, Terry
core