Results 121 to 130 of about 7,091,293 (301)

Yunus Abdullah - Use of Social Media by Businesses: A New opportunity For Consulting Services by Accounting Firms [PDF]

open access: yes, 2013
In the last 10 years, social media has been restructuring business policies and practices creating new business models. These models are shaping the internal and external aspects of businesses, improving efficiency, and hopefully yielding higher profits ...
Abdullah, Yunus
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Digital literacy’s impact on digital village participation in rural left-behind women through serial mediation of political trust and self-efficacy

open access: yesScientific Reports
Rural left-behind women, as important potential participants in Digital Village Development, face multiple challenges including limited educational resources, weak digital skills, constrained economic conditions, and traditional socio-cultural barriers ...
Xueyan Bai, Lin Yang
doaj   +1 more source

Delivering building simulation information via new communication media [PDF]

open access: yes, 2007
Often, the goal of understanding how the building works and the impact of design decisions is hampered by limitations in the presentation of performance data.
Clarke, J.A.   +3 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Traditional cloud pattern classification algorithm based on semi-supervision with Random Line Augment

open access: yesScientific Reports
The classification of traditional patterns is of great significance for their digital protection. Most studies focus on classifying patterns of different categories, while this study addresses the difficulty of classifying patterns of different types ...
Cui Chen, Hongjuan Wang
doaj   +1 more source

Editorial: Mindfulness in internet and new media. [PDF]

open access: yesFront Psychol, 2023
Liu C, Chen H, Zhuo JW, Chiou WK.
europepmc   +1 more source

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